Recombinant Human PlGF-1

PlGF-1是一种血管生成因子,属于cysteine-knot总科的增长因素。PlGF-1胎盘组织中的表达,结肠癌和乳房癌。它通过VEGFR-1 / FLT1受体和信号刺激内皮细胞增殖和迁移。重组人类PlGF-1 29.7 kDa disulfide-linked homodimeric两个132氨基酸的蛋白质多肽链。使用所有无动物生产试剂。

一.产品名称：Recombinant Human PlGF-1/重组蛋白PlGF-1

二.Catalog Number:AF-100-06

三.Synonyms:Placenta Growth Factor-1, PlGF, PGF

四.Description:

PlGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant human PlGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 132 amino acid polypeptide chains. Manufactured using all non-animal reagents.

五.AA Sequence:

MLPAVPPW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR

六.Source:E.coli

七.Purity:Greater than 95% by SDS-PAGE gel and HPLC analyses.

八.Biological Activity:

Determined by its ability to chemoattract human monocytes of using a concentration range of 1.0-10.0 ng/ml.

九.Cross Reactivity:Human