Recombinant Human EGF

EGF是一个强有力的生长因子,刺激各种上皮和上皮细胞的增殖。此外,EGF可以抑制胃液分泌,并参与伤口愈合。EGF受体信号在被称为c-erbB,这是一个类我酪氨酸激酶受体。这种受体也绑定TGF-α和VGF。重组人类EGF是6.2 kDa球状蛋白质包含53个氨基酸残基包括3分子内disulfide-bonds。。

一.产品名称：Recombinant Human EGF

二.货号Catalog Number:AF-100-15

三.同义Synonyms:Epidermal Growth Factor, Urogastrone, URG

四.描述Description:

EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant human EGF is a 6.2 kDa globular protein containing 53 amino acid residues including 3 intramolecular disulfide-bonds. .

*Animal-Free Human EGF (Catalog Number AF-100-15) has replaced Human EGF (Catalog Number 100-15)

Manufactured using all non-animal reagents.

六.AA序列AA Sequence:

NSDSECPLSH DGYCLHDGVC MYIEALDKYA CNCVVGYIGE RCQYRDLKWW ELR

七.来源Source:E.coli

八.纯度Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.

九.生物活性Biological Activity:

The ED₅₀ was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg

十.交叉性Cross Reactivity:

Cow, Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Human, Human + Mouse, Chicken