Recombinant Human KGF

FGF-7是已知的FGF家族的成员。这个家庭中发挥核心作用的蛋白质在产前发展和产后的生长和再生各种组织,通过促进细胞增殖和分化。FGF-7是一个特定的上皮细胞和角化细胞分裂素因素。 FGF-7信号通过FGFR 2 b。FGF-7肾和肺发展中所起的作用,血管再生和伤口愈合。FGF-7 18.9 kDa蛋白由163个氨基酸残基组成。使用所有无动物生产试剂。

一.产品名称：Recombinant Human KGF

二.Catalog Number:AF-100-19

三.Synonyms:Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7

四.Description:

KGF/FGF-7 is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF/FGF-7 is a mitogen factor specific for epithelial cells and keratinocytes. KGF/FGF-7 signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Recombinant human KGF/FGF-7 is a 18.9 kDa protein consisting of 163 amino acid residues. Manufactured using all non-animal reagents.

五.AA Sequence:

CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT

六.Source:E.coli

七.Purity:Greater than 95% by SDS-PAGE gel and HPLC analyses.

八.Biological Activity:

The ED₅₀ as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ≤ 10 ng/ml corresponding to a specific activity of ≥ 1 x 10⁵ units/mg.

九.Cross Reactivity:Human, Rat, Mouse