Recombinant Human MCP-1 （CCL2）

MCP的蛋白质属于CC趋化因子家族,和信号通过CCR2,MCP-1除外,其他CCR受体。MCP蛋白质chemoattract和激活单核细胞,激活T细胞,嗜碱粒细胞,NK细胞、不成熟的树突细胞。跨物种MCP家族交叉反应。重组人类MCP-1是8.6 kDa蛋白质含有76个氨基酸残基包括四个高度保守的半胱氨酸残基在CC趋化因子。使用所有无动物生产试剂。

一.产品名称：Recombinant Human MCP-1 (CCL2)/Peprotech MCP-1

二.Catalog Number:AF-300-04

三.Synonyms:Monocyte Chemotactic Protein-1, CCL2, MCAF, JE (murine)

四.Description:

The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant human MCP-1 is an 8.6 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. Manufactured using all non-animal reagents.

五.AA Sequence:

QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT

六.Source:E.coli

七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.

八.Biological Activity:

Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.

九.Cross Reactivity:Bacteria, Chicken, Monkey, Mouse, Rat, Human