10OBT001Obtustatin
【简单介绍】
【详细说明】
Obtustatin
Inhibitor of the binding of α1β1 integrin to collagen IV
抑制α1β1整合素与胶原蛋白IV结合
Obtustatin is a 41 amino acid disintegrin peptide isolated from the venom of the Vipera lebetina obtusa. It is a potent (IC50 = 2 nM) and selective inhibitor of the binding of α1β1 integrin to collagen IV. Contrary to other known disintegrins, it does not contain the classical RGD sequence. does not show inhibitory activity toward other integrins, including α2β1, αIIbβ3, αvβ3, α4β1, α5β1, α6β1, and α9β1, α4β7 integrins. potently inhibits angiogenesis in chicken and in mouse model and reduces tumor development by half.
技术资料
氨基酸序列:Cys1-Thr-Thr-Gly-Pro-Cys6-Cys7-Arg-Gln-Cys10-Lys-Leu-Lys-Pro-Ala-Gly-Thr-Thr-Cys19-Trp-Lys-Thr-Ser-Leu-Thr-Ser-His-Tyr-Cys29-Thr-Gly-Lys-Ser-Cys34-Asp-Cys36-Pro-Leu-Tyr-Pro-Gly-OH
二硫键: Cys1-Cys10, Cys6-Cys29, Cys7-Cys34 and Cys19-Cys36
长度(aa):41
分子式: C184H284N52O57S8
分子量:4393.13 Da
外观:White lyophilized solid
可溶性:aqueous buffer
CAS 号: not available
来源: Synthetic
纯度: > 97 %
产品信息
10OBT001-00100 | 0.1mg | |
10OBT001-00500 | 0.5mg | |
10OBT001-01000 | 1mg |
相关产品
- smartox 多肽毒素
- ADT001-00010AdTx1 (rho-Da1a – ρ-Da1b)
- BPX001-01000β-Pompilidotoxin
- WAG002Waglerin-1-FAM (羧基荧光素标记Waglerin-1)
- PTX003ProTx-III,新的选择性Nav1.7通道阻断剂
- OD1,有效的Nav1.7通道激活剂
- NMB001NMB-1
- MTX007-00100MT7 – Muscarinic Toxin 7(毒蕈碱毒素7)
- MEL01Melittin 蜂毒肽,蜂毒素
- MAM001-50010Mambalgin-1
- LED01-00100Leiuorotoxin-Dab7 (Lei-Dab7)
- Huwentoxin-XVI
- CRO001Crotamine响尾蛇胺
- 10VAN003Vanillotoxin 3(VaTx3)
- SAT001TMR-ShK (TMR-Stichodactyla toxin)
- 08TER001Tertiapin-Q
- 10TAM001Tamapin
- SCT01Stromatoxin-1 / ScTx1
- 08SHK001Stichodactyla toxin(ShK)
- 011PUR001Purotoxin-1
- 13PCT001Psalmotoxin 1/ PcTx1
- 07PTX002Protoxin II / ProTx-II
- 12PTX001Protoxin I / ProTx-I
- 13PHX003Phrixotoxin-3 /Paurtx-3
- PHX002-50010Phrixotoxin-2 / PaTx2
- 10OBT001Obtustatin
- 11CAS001Morphiceptin(吗啡感受素:阿片μ受体激动剂)
- 08MAR001Maurotoxin
- 07MAU001Maurocalcine
- 11CON014Lys-conopressin G(加压素样肽)
- 10LEI001Leiurotoxin 1 / Scyllatoxin
- 08NEU001HsTx-1
- 11GUA002Guangxitoxin 1E(GxTx-1E)
- 08GSM001GsMTx4
- 12GSF002GsAF-II
- 12GSF001GsAF-I
- 10GTX002GaTx2
- 13GTX001GaTx1
- 08CON009Conantokin-G(芋螺抑制肽-G)
- 11CHA001Charybdotoxin /ChTx
请输入产品关键字:
邮编:100083
联系人:尤女士
电话:4008858216
传真:
手机:13581534696
留言:发送留言
个性化:www.qbiotec.com
网址:www.qbiotec.com
商铺:https://www.chem17.com/st289923/