13AGI002Agitoxin-2
【简单介绍】
【详细说明】
Agitoxin-2
Blocker of Kv1.1 and Kv1.3 channels
钾离子通道Kv1.1 和Kv1.3阻断剂
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. inhibits Kv1.3 with an IC50 value of around 200 pM and Kv1.1 with an IC50 value of around 140 pM. This peptide toxin was originally isolated from the venom of the Israeli scorpion L. quinquestriatus hebraeus.
技术资料
氨基酸序列:
Gly-Val-Pro-Ile-Asn-Val-Ser-Cys8-Thr-Gly-Ser-Pro-Gln-Cys14-Ile-Lys-Pro-Cys18-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys28-Met-Asn-Arg-Lys-Cys33-His-Cys35-Thr-Pro-Lys-OH
二硫键:Cys8-Cys28; Cys14-Cys33; Cys18-Cys35
长度 (aa): 38
分子式: C169H278N54O48S8
分子量:4090.89 Da
外观: White lyophilized solid
可溶性:water and saline buffer
CAS 号: 168147-41-9
来源: Synthetic
纯度: > 97 %
产品信息
13AGI002-00100 | Agitoxin 2 | 0.1mg |
13AGI002-00500 | Agitoxin 2 | 0.5mg |
13AGI002-01000 | Agitoxin 2 | 1mg |
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