NUCLEOSHELL® 核-壳硅胶键合相液相色谱柱
- 公司名称 北京科益恒达科技有限公司
- 品牌 MN/德国
- 型号
- 产地
- 厂商性质 生产厂家
- 更新时间 2018/1/3 15:34:07
- 访问次数 489
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供货周期 | 现货 |
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产品特点:
NUCLEOSHELL® core-shell silica phases for HPLC |
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Features |
| Core-shell technology: Highest efficiency compared to traditional totally porous materials Pore size 90 Å; particle size 2.7 µm (core 1.7 µm); specific surface 130 m2/g Lower back pressure also allows use on conventional LC systems Pressure stability up to 600 bar |
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Summary of available NUCLEOSHELL® phases | ||||||
Phase | Modification | % C | pH range | Particle size [µm] | USP | Structure |
RP 18 | Octadecyl, multi-endcapping | 7.5 | 1–11 | 2.7 | L1 | |
Phenyl-Hexyl | Phenyl-Hexyl, multi-endcapping | 4.5 | 1-10 | 2,7 | L11 | |
PFP | Pentafluorophenyl, multi-endcapping | ~ 3 | 1–9 | 2.7 | L43 | |
HILIC | Ammonium – sulfonic acid | 1.3 | 2–8.5 | 2.7 | – |
Demands on HPLC separations are constantly increasing with respect to separation efficiency and detection limits as well as concerning the time requirements for each analysis. Core-shell technology sets new standards for increasing efficiency in research and quality control. |
Benefits of core-shell technology | Core-shell particles vs. | |
Short diffusion paths | ||
Rapid mass transfer (C term of the Van Deemter equation) | ||
High flow velocity without peak broadening for fast LC | ||
Narrow particle size distribution (d90/d10 ~ 1.1) | ||
Stable packing | ||
High heat transfer | ||
Minimized influence of frictional heat | ||
Column efficiency of NUCLEOSHELL® ~ 250000/m (HETP ~ 4 µm) |
Resolution Rs as function of particle size | ||
Columns: | 50 x 4 mm | |
Eluent: | acetonitrile – water (60:40, v/v) | |
Peaks: | Better resolution at |