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目录:杭州斯达特生物科技有限公司>>抗体/抗原>>流式抗体>> S0B5517PE-Cy7 Rat Anti-Mouse CD4 Antibody (S-R382)

PE-Cy7 Rat Anti-Mouse CD4 Antibody (S-R382)
  • PE-Cy7 Rat Anti-Mouse CD4 Antibody (S-R382)
参考价 600
具体成交价以合同协议为准
参考价 600
具体成交价以合同协议为准
  • 品牌 Starter/斯达特
  • 型号 S0B5517
  • 厂商性质 生产商
  • 所在地 杭州市
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更新时间:2025-07-13 12:22:16浏览次数:156评价

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PE-Cy7 Rat Anti-Mouse CD4 Antibody (S-R382)

CD4 is a glycoprotein that functions as a co-receptor for the T-cell receptor (TCR) and is primarily expressed on the surface of helper T cells, monocytes, macrophages, and dendritic cells. It is a member of the immunoglobulin superfamily, consisting of four immunoglobulin domains (D1 to D4) that interact with MHC class II molecules on antigen-presenting cells. This interaction, mediated by the D1 domain of CD4, ensures that T cells recognize antigens presented by MHC II. The cytoplasmic tail of CD4 contains motifs that recruit the tyrosine kinase Lck, which amplifies T cell activation signals. Additionally, CD4 is crucial in the immune response, as it helps activate CD4+ T helper cells, which in turn stimulate other immune cells to combat infections. However, CD4 is also the primary receptor for HIV, allowing the virus to enter host T cells and cause immunodeficiency.

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