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目录:杭州斯达特生物科技有限公司>>抗体/抗原>>流式抗体>> S0B5519PercP-Cy5.5 Mouse Anti-Human CD14 Antibody (S-631-50)

PercP-Cy5.5 Mouse Anti-Human CD14 Antibody (S-631-50)
  • PercP-Cy5.5 Mouse Anti-Human CD14 Antibody (S-631-50)
参考价 1250
具体成交价以合同协议为准
参考价 1250
具体成交价以合同协议为准
  • 品牌 Starter/斯达特
  • 型号 S0B5519
  • 厂商性质 生产商
  • 所在地 杭州市
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更新时间:2025-07-13 12:18:02浏览次数:77评价

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PercP-Cy5.5 Mouse Anti-Human CD14 Antibody (S-631-50)

CD14 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein primarily expressed on monocytes, macrophages, and some granulocytes. It functions as a pattern recognition receptor (PRR) and plays a crucial role in the innate immune response by recognizing bacterial lipopolysaccharides (LPS), pathogen-associated molecular patterns (PAMPs), and damage-associated molecular patterns (DAMPs). CD14 exists in two forms: membrane-bound CD14 (mCD14) and soluble CD14 (sCD14), which can be secreted by activated cells. It acts as a co-receptor for Toll-like receptor 4 (TLR4) and enhances the immune response to LPS by facilitating its delivery to the TLR4-MD2 complex. Additionally, CD14 is involved in TLR4-independent signaling pathways and contributes to tissue homeostasis by promoting the clearance of apoptotic cells.

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