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目录:杭州斯达特生物科技有限公司>>抗体/抗原>>配对抗体>> S0B3403IL-29/IL-28 Recombinant Rabbit mAb (SDT-1838-9)

IL-29/IL-28 Recombinant Rabbit mAb (SDT-1838-9)
  • IL-29/IL-28 Recombinant Rabbit mAb (SDT-1838-9)
参考价 5000
具体成交价以合同协议为准
参考价 5000
具体成交价以合同协议为准
  • 品牌 Starter/斯达特
  • 型号 S0B3403
  • 厂商性质 生产商
  • 所在地 杭州市
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更新时间:2025-07-12 18:38:33浏览次数:42评价

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IL-29/IL-28 Recombinant Rabbit mAb (SDT-1838-9)

IL-28A, IL-28B, and IL-29, also named interferon-lambda 2 (IFN-lambda 2), IFN-lambda 3, and IFN-lambda 1, respectively, are newly identified class II cytokine receptor ligands that are distantly related to members of the IL-10 family (11-13% a.a. sequence identity) and the type IIFN family (15-19 % a.a. sequence identity). The expression of IL-28A, B, and IL-29 is induced by virus infection or double-stranded RNA. All three cytokines exert bioactivities that overlap those of type I IFNs, including antiviral activity and upregulation of MHC class I antigen expression. The three proteins signal through the same heterodimeric receptor complex that is composed of the IL-10 receptor lambda (IL-10 R beta) and a novel IL-28 receptor alpha (IL-28 R alpha, also known as IFN-lambda R1). Ligand binding to the receptor complex induces Jak kinase activation and STAT1 and STAT2 tyrosine phosphorylation.

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