目录:亚科因(武汉)生物技术有限公司>>细胞因子及蛋白>>细胞因子>> Mouse VEGF164 Protein, His tag重组小鼠源血管内皮生长因子,His-标签(VEGF164)
产品英文名称 | Mouse VEGF164 Protein, His tag |
产品中文名称 | 重组小鼠源血管内皮生长因子,His-标签(VEGF164) |
别名 | VEGF-AA, Vascular endothelial growth factor A, Vascular permeability factor, VPF, VEGFA, VEGFA164, VEGF164 |
表达宿主 | 大肠杆菌 |
种属 | 小鼠 |
序列 | 氨基酸序列来源于:小鼠源VEGF164 (Ala27-Arg190) (Q00731-2) 表达的蛋白片段。 |
活性 | Testing in Progress |
蛋白长度 | 重组小鼠 VEGF165 由165个氨基酸组成,预测分子量为19.4 KD。 |
纯度 | > 99 % ,使用SDS-PAGE检测 |
特点&优势 | 通过LAL法测定,每微克蛋白里内毒素含量<0.1>0.1> |
产品形式 | 冻干粉,冻干缓冲液为无菌的20 mM Tris,150 mM NaCl,pH 8.0。 |
基因ID | 22035 |
蛋白序列链接 | /uniprotkb/Q00731 |
使用中注意事项 | 开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于106 µg/mL。客户可根据后续的实验需求,进行进一步的稀释。 |
保存建议 | 本产品为冻干粉形式,建议:将冻干粉产品保存于-20℃以下的干燥环境中。本产品溶解之后,可在4℃保存2-7天,长期使用请置于-20℃以下。为长期保存,推荐添加载体蛋白(0.1% HSA或者BSA),并酌情分装保存,避免反复冻融。 |
运输条件 | 冰袋运输(蓝冰) |
警告 | 本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何或许可证。对于使用本产品可能发生的侵权或其他违规行为,我们不承担任何责任。 |
背景 | Mouse Vascular endothelial growth factor (VEGF or VEGFA), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the PDGF/VEGF growth factor family that is characterized by a cystine knot structure formed by eight conserved cysteine residues. Alternately spliced isoforms of 120, 164 and 188 aa found in mouse. VEGF binds the type I transmembrane receptor tyrosine kinases VEGF R1 (also called Flt1) and VEGF R2 (Flk/KDR) on endothelial cells.Although affinity is highest for binding to VEGF R1, VEGF R2 appears to be the primary mediator of VEGF angiogenic activity. VEGF is required during embryogenesis to regulate the proliferation, migration, and survival of endothelial cells.It may play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. |
Fig.Mouse VEGF164 Protein, His tag