Nutlin-3 返回列表页

举报评价

参考价

面议

具体成交价以合同协议为准

产品型号27711

品牌BPS Bioscience

厂商性质生产商

所在地

在线询价加入对比查看联系电话

更新时间：2023-12-19 22:38:58浏览次数：120次

联系我时，请告知来自化工仪器网

同类优质产品更多>

4-(4-(4-(3-fluorobenzyloxy)-3-chlor

参考价面议
(+)-JQ1

参考价面议
(+)-JQ1

参考价面议
(+)-JQ1

参考价面议
(-)-JQ1

参考价面议

产品分类品牌分类

Inhibitors / Activators

全部产品列表

产品简介

●Purchase●DescriptionCis-imidazolineanalogthatinhibitstheinteractionbetweenp53anditsnegativeregulatorMDM2(IC50=0

详情介绍

●

Purchase

●

Description

Cis-imidazoline analog that inhibits the interaction between p53 and its negative regulator MDM2 (IC50 = 0.09 μM). It induces the expression of p53-regulated genes and exhibits potent antiproliferative activity in cells with functional p53, but not in cells with mutated p53. Nutlin-3 also inhibits the growth of human tumor xenografts in nude mice by 90% at a dose of 200 mg/kg.

●

Synonyms

(±)–4–[4,5–Bis(4–chlorophenyl)–2–(2–isopropoxy–4–methoxy–phenyl)–4,5–dihydro–imidazole–1–carbonyl]–piperazin–2–one