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产品型号27777-2

品牌BPS Bioscience

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Inhibitors / Activators

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●Purchase●DescriptionVER-155002isasmallmolecule,ATP-derivativeinhibitorofHSP70(IC50=500nM)

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Description

VER-155002 is a small molecule, ATP-derivative inhibitor of HSP70 (IC50 = 500 nM). The compound inhibits proliferation of several colon and breast cancer cell lines, induces caspase dependent apoptosis in BT474 cells and down regulates expression of Her2 and Raf-1 in HCT116 cells.

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Synonyms

adenosine-derived inhibitor; VER155008; VER-155008; me 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethyl]benzonitrile

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