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AR-42 (OSU-HDAC42)

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更新时间:2023-12-19 23:32:32浏览次数:226次

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保存条件:Roomtemp
  • 保存条件:

    Room temp. (continental US) or gel packs

  • 保质期:

    Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

  • 英文名:

    AR-42 (OSU-HDAC42)

  • 数量:

    1

  • 供应商:

    BPS Bioscience Inc.

  • CAS号:

    /

  • 规格:

    5 mg

AR-42 (also known as OSU-HDAC42), a derivative of hydroxamate-tethered phenylbutyrate is a broad-spectrum deacetylase inhibitor of both histone and non-histone proteins. AR-42 treatment induces histone hyperacetylation and p21WAF/CIP1 overexpression, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells.
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