目录:MedChemExpress LLC>>生化试剂>> Adalimumab (anti-TNF-α) | MCE
CAS | 331731-18-1 | 纯度 | 99.62% |
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供货周期 | 现货 | 规格 | 10 mg |
货号 | HY-P9908A | 应用领域 | 医疗卫生,化工,生物产业,制药/生物制药 |
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CAS No. : 331731-18-1
产品活性:Adalimumab (anti-TNF-α) is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).
研究领域:Apoptosis
作用靶点:TNF Receptor
In Vitro: Treatment of HUVECs with Adalimumab for up to 12 hours shows no adverse effect on their cell viability, even with a 10-fold higher concentration of Adalimumab (anti-TNF-α) than used in this study.
In Vivo: The elimination half-life (t1/2) of Adalimumab (anti-TNF-α) is long (~20 days). The enriched fluorescent-labelled adalimumab (anti-TNF-α) is observed mainly in major Oil red O-positive lesions documenting good tissue penetration of the drug into the atherosclerotic plaque, without background fluorescence of the vessel wall after vehicle control injection into hypercholesterolemic Ldlr-/- mice.
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