Rocilinostat (ACY-1215) 返回列表页

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产品型号27644-1

品牌BPS Bioscience

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更新时间：2024-11-25 16:36:16浏览次数：98次

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Inhibitors / Activators

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●Purchase●DescriptionRocilinostat,alsoknownasACY-1215,isaselectiveHDAC6inhibitorwithIC50of5nM

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Description

Rocilinostat, also known as ACY-1215, is a selective HDAC6 inhibitor with IC50 of 5 nM. It is over 10-fold more selective for HDAC6 than HDAC1, 2, 3 (class I HDACs) with slight activity against HDAC8, and minimal activity against HDAC4, 5, 7, 9, 11, SIRT1, and SIRT2.

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Synonyms

Rocilinostat; ACY-1215; N-[7-(hydroxyamino)-7-oxoheptyl]-2-(N-phenylanilino)pyrimidine-5-carboxamide

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