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BPS Bioscience
BPS Bioscience的细胞信号通路筛选和检测服务
To determine effectors of cell signaling pathways in the context of intact functioning cells, cell-based reporter assays are an ideal option. Using luciferase reporters downstream of a pathway-specific promoter response element, signaling activity can be conveniently measured by the output of luciferase activity. The system can be applied across a wide variety of cell types and signaling pathways and allows for high throughput screening of large libraries of compounds for inhibitory or activating function. Alternatively, fluorescent proteins such as eGFP and RFP can be used to visualize live cellular readouts.
We offer rapid and dependable screening and profiling services for cell signaling pathway effectors. Our team of experts, using our broad portfolio of in-house developed cell-based assay kits, can provide:
Screening for active compounds (small molecules, peptides, or antibodies)
Determination of IC50 or EC50
Project guidance and questions answered in a timely manner
Delivery of detailed results promptly and on time
If your desired cell-based assay is not available, we may be able to develop a custom product for you.
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AP1 Reporter (JNK Pathway) |
NFAT Reporter (Jurkat) |
ARE Reporter (Nrf2 Antioxidant Pathway) | Notch1/CSL Reporter (Notch Signaling Pathway) |
CREB/CRE Reporter (cAMP/PKA Pathway) | Myc Reporter (Myc Signaling Pathway) |
FOXO Reporter (PI3K/AKT Pathway) |
RARα Reporter |
Gli Reporter (Hedgehog Pathway) | RARβ Reporter |
IRF Reporter (cGAS-Sting Signaling Pathway) |
RARγ Reporter |
ISRE Reporter (JAK Pathway) | SBE Reporter (TGF/SMAD Signaling Pathway) |
NF-κB Reporter (A549) | SRE Reporter (ERK Pathway) |
NF-κB Reporter (HCT-116) |
STAT3 Reporter |
NF-κB Reporter (HEK293) | TEAD Reporter (Hippo Pathway) |
NF-κB Reporter (Jurkat) | TCF/LEF Reporter (Wnt Signaling Pathway) |
NF-κB Reporter (NIH-3T3) | NF-κB Reporter (THP-1) |
如果您需要了解更多关于我们的服务的信息,请联系info。
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