This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads
Human,Mouse,Rat
WB,IHC-P,IHC-F,Flow-Cyt,IF
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.