EIF4B is required for the binding of mRNA to ribosomes. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F.
Human,Mouse,Rat
WB,IHC-P,IHC-F,IF
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.