Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Human,Mouse,Rat
WB,IHC-P,IHC-F,ICC/IF,IF,IP,Flow-Cyt
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.