Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.
Human,Mouse,Rat
WB,IHC-P,IHC-F,ICC/IF,IF,IP,Flow-Cyt
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.