UM-UC-3人膀胱移行细胞癌_普通细胞-上海富雨生物科技有限公司

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人膀胱移行细胞癌UM-UC-3

种属	人
别称	UMUC-3; UM-UC3; UMUC3; UC-3; University of Michigan-Urothelial Carcinoma-3
组织来源	膀胱
疾病	移行细胞癌
传代比例/细胞消化	1:2传代，消化2-3分钟
培养基配置	MEM培养基；10%胎牛血清；1%双抗
简介	Derived from a urinary bladder transitional cell carcinoma from a human male. These cells are tumourigenic in nude mice when 10E7 cells are inoculated subcutaneously. Hypertriploid. The modal chromosome number was 80, occurring in 42% of cells. Cells with 78 chromosomes also occurred at a high frequency. The rate of cells with higher ploidies was 2.5%. There were 30 or more marker chromosomes in each cell. They included der(1)t (1;?) (p32;?), ?t(1p5p), i(3q), t(7q14q), ?t(2p3p) ａnd others. The X and N3 had single copy per cell, and others were generally two or three copies per cell.
形态	上皮细胞样
生长特征	贴壁生长
倍增时间	每周 2 至 3 次
致瘤性	Yes, Tumors developed within 21 days at 99% frequency (5/5) in nude mice inoculated subcutaneously with 10(7) cells.
STR	Amelogenin: X CSF1PO: 10,11 D13S317: 8 D16S539: 8,9 D5S818: 12 D7S820: 8,9 THO1: 6,9 TPOX: 10 vWA: 17
培养条件	气相：空气，95% ；二氧化碳，5%。温度：37摄氏度，培养箱湿度为70%-80%。
冻存条件	冻存液：90%FBS ，DMSO 10%, 或使用非程序冻存液：货号JY-H040
保藏机构	ATCC; CRL-1749
产品使用	于科学研究，不可作为动物或人类疾病的治疗产品使用。

Compared with the control group，the expression levels of Afamin and DBP in serum of the POI group were significantly increased (P＜0．05) ; the expression levels of serum Afamin and DBP were positively correlated with FSH and E2 (P＜ 0．05) ，but negatively correlated with AMH (P＜0. 05) ;