IPEC-J2 猪小肠上皮细胞_ATCC细胞-上海富雨生物科技有限公司

IPEC-J2 猪小肠上皮细胞返回列表页

参考价

面议

具体成交价以合同协议为准

产品型号

品牌

厂商性质生产商

所在地

在线询价加入对比查看联系电话

更新时间：2025-04-24 11:31:03浏览次数：53次

联系我时，请告知来自化工仪器网

产品名称：IPEC-J2 猪小肠上皮细胞、IPEC-J2 猪小肠上皮细胞、IPEC-J2 猪小肠上皮细胞、IPEC-J2 猪小肠上皮细胞；

猪正常肠上皮细胞IPEC-J2

种属	猪
别称	IPECJ2; Intestinal Porcine Epithelial Cell line-J2
组织来源	肠（空肠）
疾病	正常
传代比例/细胞消化	1:2传代，消化1-3分钟
培养基配置	DMEM培养基；10%胎牛血清；1%双抗
简介	该细胞从一只新生的未感染猪空肠分离的正常肠上皮细胞中建立，经历一个自发的分化过程，在1-2周内形成具有低或高跨上皮电阻（TEER）的极化单层，这取决于加入培养基的血清类型。
形态	上皮细胞样
生长特征	贴壁生长
倍增时间	每周 2 至 3 次
培养条件	气相：空气，95% ；二氧化碳，5%。温度：37摄氏度，培养箱湿度为70%-80%。
冻存条件	冻存液：90%FBS ，DMSO 10%, 或使用非程序冻存液：货号JY-H040
保藏机构	DSMZ; ACC-701
产品使用	于科学研究，不可作为动物或人类疾病的治疗产品使用。

The aim of this study is to determine whether the pretreatment CD8+PD-1+ to CD4+PD-1+ (PERLS) ratio is an independent risk prognostic factor of advanced melanoma patients. We retrospectively analyzed the efficacy and flow cytometry data from advanced melanoma patients who received PD-1 inhibitor as monotherapy between January 1, 2018 and January 26, 2022. Fifty-nine patients were enrolled, the PERLS cutoff was 1.125. PERLS did not correlate with clinical characteristics but were significantly associated with baseline CD8+, CD4+, and CD8+PD-1+ T cells. The mean overall survival and the progression-free survival were 45.8 and 17.1 months for the low PERLS group (n = 39), compared with 29.9 (P = 0.001) and 9.7 (P = 0.003) months for the high PERLS group (n = 20), respectively. Pretreatment PERLS might contribute to selecting patients before receiving anti-PD-1 therapy.