ZIP Kinase抗体，凋亡相关蛋白激酶3抗体

产品名称：Rabbit Anti-ZIP Kinase  antibody

Rabbit Anti-ZIP Kinase 

别名：DAPK3; Death associated protein kinase 3; DAP kinase 3; DAP like kinase; Dapk 3; Dapk3; Death associated kinase 3; Death associated protein kinase 3; Dlk; EC 2.7.11.1; FLJ36473; ZIP; ZIP kinase; ZIPK; DAPK3_HUMAN.  

来源：Rabbit

克隆类型：Polyclonal

浓度：1mg/ml

亚型：IgG

应用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反应: predicted: Human,Mouse,Rat,Rabbit,Cow,Chicken,Dog,Horse

理论分子量：52kDa

免疫原：KLH conjugated synthetic peptide derived from human ZIP Kinase

保存：-20℃
保质期：1年

产品名称：Anti-ZIP Kinase antibody

Mouse Anti-ZIP Kinase 

别名：DAPK3; Death associated protein kinase 3; DAP kinase 3; DAP like kinase; Dapk 3; Dapk3; Death associated kinase 3; Death associated protein kinase 3; Dlk; EC 2.7.11.1; FLJ36473; ZIP; ZIP kinase; ZIPK; DAPK3_HUMAN. 

来源：Mouse

克隆类型：Monoclonal

浓度：1mg/ml

亚型：IgG

应用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500 

反应:  Human

理论分子量：52kDa

免疫原：KLH conjugated synthetic peptide derived from human ZIP Kinase

保存：-20℃
保质期：1年

 Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certainserine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N terminal kinase domain and a C terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREBfamily. ZIP kinase has high sequence homology to DAP kinase (death associated protein kinase), which is a mediator of apoptosis induced by gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis through their catalytic activities. The messenger RNA was ubiquitously expressed in various tissues.

Recombinant human ZIP Kinase   

DAPK3; Death associated protein kinase 3; DAP kinase 3; DAP like kinase; Dapk 3; Dapk3; Death associated kinase 3; Death associated protein kinase 3; Dlk; EC 2.7.11.1; FLJ36473; ZIP; ZIP kinase; ZIPK; DAPK3_HUMAN.

浓度：1mg/ ml

来源：Recombinant Human

纯度：≥90% SDS-PAGE

表达系统：Baculovirus infected Sf9 cells

标签：GST tag N-Terminus  

蛋白长度：Full length protein

氨基酸：1 to 454

内毒素水平：<1.000 Eu/µg

纯化方法：HPLC

应用：SDS-PAGE，Western blot，ELISA

Biological activity,immunology research

保存：-20℃

保质期：1年

 Serine/threonine kinase which acts as a positive regulator of apoptosis. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection.