盐酸依特卡肽 1334237-71-6，KAI-4169 返回列表页

盐酸依特卡肽 1334237-71-6，KAI-4169

英文名：Etelcalcetide hydrochloride

(6R,9R,12R,15R,18R,21R,24S,29R)-24-Acetamido-1,29-diamino-12,15,18-tris(3-carbamimidamidopropyl)-6-carbamoyl-1-imino-9,21-dimethyl-8,11,14,17,20,23-hexaoxo-26,27-dithia-2,7,10,13,16,19,22-heptaazatriacontan-30-oic acid hydrochloride (1:1)

AMG 416

velcalcetide hydrochloride

etelcalcetide hydrochloride

KAI-4169

UNII:72PT5993DU

AMG-416

中文名：盐酸依特卡肽

CAS：1334237-71-6

分子式：C38H73N21O10S2.xClH

分子量：1084.712

结构式：

***质量：1083.505737

描述：Etelcalcetide hydrochloride (AMG 416 hydrochloride) 是一种合成肽，有钙敏感受体 (CaSR) 活化剂的作用。Etelcalcetide hydrochloride 可有效降低接受血液透析的继发性甲状旁腺功能亢进患者的甲状旁腺*** (PTH) 浓度。

参考文献：

[1]. Block GA, et al. Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial. JAMA. 2017 Jan 10;317(2):156-164.

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盐酸依特卡肽 1334237-71-6，KAI-4169