DOTA-GRGDSP，DOTA偶联多肽GRGDSP

DOTA-GRGDSP，DOTA偶联多肽GRGDSP

名称：DOTA-GRGDSP，DOTA偶联多肽GRGDSP

GRGDSP 是一种合成的线性RGD肽，是一种整联蛋白 (integrin) 抑制剂。

GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.

It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor which includes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis[1]. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. GRGDSP can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization.

中文名称：GRGDSP

英文名：GRGDSP

CAS号：91037-75-1

单字母：H2N-GRGDSP-OH

三字母：H2N-Gly-Arg-Gly-Asp-Ser-Pro-COOH

氨基酸个数：6

分子式：C22H37N9O10

平均分子量：587.58

***分子量：587.27

等电点(PI)：6.34

pH=7.0时的净电荷数：-0.02

平均亲水性：2.1

疏水性值：-1.87

来源：Synthetic

纯度：95%、98%

盐体系：可选TFA、HAc、HCl或其它

生成周期：2-3周

相关试剂列表：

DOTA-Stearyl-R8 DOTA偶联细胞穿膜肽Stearyl-R8

DOTA-HIV-Tat DOTA偶联细胞穿膜肽HIV-Tat

DOTA-PTD-5 DOTA偶联细胞穿膜肽PTD-5

DOTA-TAT(48-60)-NH2 DOTA偶联细胞穿膜肽TAT(48-60)-NH2

DOTA-Tat(48-61) DOTA偶联细胞穿膜肽Tat(48-61)

DOTA-plsl DOTA偶联细胞穿膜肽plsl

DOTA-VP22 DOTA偶联细胞穿膜肽VP22

DOTA-SynB1 DOTA偶联细胞穿膜肽SynB1

DOTA-L17E DOTA偶联细胞穿膜肽L17E胞质输送肽

DOTA-P-alpha DOTA偶联细胞穿膜肽P-alpha

DOTA-Transportan DOTA偶联细胞穿膜肽Transportan

DOTA-POD DOTA偶联眼部转运肽POD

DOTA-RVG DOTA偶联狂犬病病毒肽RVG

DOTA-B6 peptide DOTA偶联细胞渗透肽B6