1565798-78-8，ACI，DOTA系列螯合剂

1565798-78-8，ACI，DOTA系列螯合剂1,4,7,10-四氮杂环十二烷-1,4,7,10-四乙酸（DOTA）是一种大环络合剂。通过螯合64铜放射性同位素，它已被用于碳纳米管生物结合物的放射性标记。在临床放射中，DOTA可被N-羟基磺基琥珀酰亚胺激活，与单克隆结合。

名称：ACI

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid

10-[2-[[3-[(2-Methyl-1-oxo-2-propen-1-yl)amino]propyl]amino]-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

CAS：1565798-78-8

化学式：C23H40N6O8

分子量：528.2908

结构式以及核磁图谱：

LCMS分析报告：

1565798-78-8，ACI，DOTA系列螯合剂产品简介：1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) is a macrocyclic complexing agent. It has been used for radiolabeling of carbon nanotube bioconjugates by chelating 64 Cu radioisotope. DOTA can be activated with N -hydroxysulfosuccinimidyl for conjugation with monoclonal antibodies in clinical radioimmunotherapy.

相关化合物：

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid

217973-03-0

gadolinium(III) 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

112188-16-6

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, triMethyl ester

131934-31-1

10-phosphonomethyl-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

677335-18-1

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-(2-aMinoethyl)-

114873-43-7

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Tri-tert-butyl Ester

122555-91-3

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Tri-tert-butyl Ester

18271-97-1

10-(3,6,9-trioxatridecyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid

686289-85-0

1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 1,4,7-tris(phenylmethyl) ester

957130-00-6