英文名：IR-825

3-[(4-Carboxyphenyl)methyl]-2-[2-[3-[2-[3-[(4-carboxyphenyl)methyl]-1,3-dihydro-1,1-dimethyl-2H-benz[e]indol-2-ylidene]ethylidene]-2-chloro-1-cyclohexen-1-yl]ethenyl]-1,1-dimethyl-1H-benz[e]indolium
产品名称：3-[(4-羧基苯基)甲基]-2-[2-[3-[2-[3-[(4-羧基苯基)甲基]-1,3-二氢-1,1-二甲基-2H-苯并[e]吲哚-2-亚基]亚乙基]-2-氯-1-环己烯-1-基]乙烯基]-1,1-二甲基-1H-苯并[e]吲哚鎓
CAS：1558079-49-4

分子式：C54H48ClN2O4

分子量：824.42
结构式：

IR-825, after encapsulated into nanoparticles may be useful for cancer photothermal and photodynamic therapy. IR-825 nanoparticles showed pH-dependent fluorescence emission and excellent near-infrared (NIR) irradiation of cancer cells targeted in vitro to provide cytotoxicity. IR-825 nanoparticles showed efficient tumor homing together with rapid renal excretion behaviors, as revealed by MR imaging and confirmed by biodistribution measurement. Notably, when irradiated with an 808 nm laser, tumors on mice with IR-825 nanoparticle injection are compley eliminated without recurrence within 60 days, demonstrating the high efficacy of photothermal therapy.

供应商：陕西新研博美生物科技有限公司

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