Lopinavir 返回列表页

仅用于工业应用或科学研究，不可用于人类或动物的临床诊断或治疗，非药用.Lopinavir （ABT-378） is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity[1][2]. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 μM