Ganglioside GT1b . trisodium salt (bovine brain)_小分子化合物-深圳欣博盛生物科技有限公司

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参考价: ￥ 5557

订货量: ≥1 件

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品牌Enzo Life Sciences

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更新时间：2022-01-27 17:31:05浏览次数：802次

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供货周期	一个月	规格	1*5mg
货号	ALX-302-011-M005	应用领域	生物产业
主要用途	科研

供货周期

一个月

规格

1*5mg

货号

ALX-302-011-M005

应用领域

生物产业

主要用途

科研

Ganglioside GT1b . trisodium salt (bovine brain)

Product Details

Alternative Name:	GT1b . 3Na (bovine brain), Trisialoganglioside GT1b . 3Na (bovine brain)

Sequence:	[II³(Neu5Ac)2, IV³(Neu5Ac)GgOse4Cer] [[α-Neu5Ac-(2→3)]-β-Gal(1→3)-β-GalNAc-(1→4)-[α-Neu5Ac-(2→8)-α-Neu5Ac-(2→3)]-β-Gal-(1→4)-β-Glc-(1→1')-Cer]

Formula:	C95H162N5O47 . 3Na

MW:	2126.3 . 69.0 (calculated on sphingosine C18:1 and stearic acid)

CAS:	59247-13-1

Purity:	≥98% (TLC)

Appearance:	White solid.

Solubility:	Soluble in chloroform/methanol/DI water, 2:1:0.1; forms micellar solution in water.

Shipping:	Ambient

Long Term Storage:	-20°C

Regulatory Status:	RUO - Research Use Only

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Product Literature References

GT1b-induced neurotoxicity is mediated by the Akt/GSK-3/tau signaling pathway but not caspase-3 in mesencephalic dopaminergic neurons: E.S. Chung, et al.; BMC Neurosci. 11, 74 (2010), Abstract;

Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex: M. Favaron, et al.; PNAS 85, 7351 (1988), Abstract;

General Literature References

Botulinum neurotoxin: a marvel of protein design: M. Montal; Annu. Rev. Biochem. 79, 591 (2010), Abstract; Full Text

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