基底膜刚度细胞牵张培育装置系统，基底膜弹性可调细胞牵张拉伸动态培养或静态培养（1-180kpa）,适合原代和干细胞牵张拉伸培养，BioFlex CellSoft培养板是当今wei一可在商业上可行的可施加细胞拉伸负荷的柔软表面。

美国Flexcell细胞应力加载培养与实时观察分析系统，包括：
1.1.FX-5000T体外细胞拉应力加载培养与实时观察分析系统
1.2.FX-5000C细胞组织压应力加载培养与实时观察分析系统
1.3.FX-5000TT细胞组织三维拉应力加载培养与实时观察分析系统
1.4.STR-4000流体剪切应力加载培养与实时观察分析系统。

其产品成熟度高、成功应用文献量达4000多篇，国内有包括上海交通大学、复旦大学、同济大学、上海第九医院、中科院力学所、北京大学第三医院、北航生物与医学工程学院、都医科大学、广州医科大学、南方科技大学、福建协和医院、南方医科大学近100家成功高校、医院及基础科研单位使用，无技术风险和使用风险，flexcell体外高通量细胞牵张拉伸力、压应力以及流体剪切力加载培养系统已成为细胞力学体外加载模型的黄金标准，是细胞组织力学研究者的shou选。

CellSoft™ Soft Substrate References

Key References:

Buxboim et al., How deeply do cells feel:methods for thin gels. J Phys Condens matter. 22: 1-19, 2010.

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Chodhury et al., Soft substrates promote homogeneous self-renewal of embryonic stem cells via down regulating cell-matrix tractions. PLOS 1 5: 1-10, 2010.

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Engle et al., Matrix elasticity directs stem cell lineage specification. Cell 126: 677-689, 2006.

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Hirata and Yamaoka. Effect of stem cell niche elasticity/ECM protein on the self-beating cardiomyocyte differentiation of iPS cells at different stages. Acta Biomat. 65: 44-52, 2018

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Megone et al., Impact of surface adhesion and sample heterogeneity on the multiscale mechanical characterization of soft biomaterials. Sci Rep 8: 6780, 2018.

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Ou et al., Visualizing mechanical modulation of nanoscale organization of cell-matrix adhesions. Integr. Biol. 8: 795-804,2016.

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Palchesko et al., Development of polydimethylsiloxane substrates with tunable elastic modulus to study cell mechanobiology in muscle and nerve. PLOS 1 7: 1-13, 2012

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Smith et al., Mechanosensing of matrix by stem cells: from matrix heterogeneity, contractility and the nucleus in pore-migration to cardiogenesis and muscle stem cells in vivo. Sem Cell Devtbio. 71: 84-98, 2017

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Solon et al., Fibroblast adaptation andstiffness matching to soft elastic substrates. Biophys J. 93: 4453-4461, 2007.

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Thomas et al., Measuring the mechanical properties of living cells using atomic force microscopy. J Visual Exp. 76:1-8, 2013.

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Vertelov et al., Rigidity of silicone substrates controls cell spreading and stem cell differentiation. Sci Rep. 6:1-10, 2016.