详细介绍
滤光片集成微流控芯片
这些模块化微流控芯片设计用于各种类型过滤器和培养基贴片的可逆集成(需单独订购)。该装置由两个PC(聚碳酸酯)塑料板组成,每个板上有四个用于可逆装配的集成磁铁和一个弹性PDMS薄膜,以确保良好的密封性。芯片上部的Luer连接器允许在实验期间进行液体灌注和动态流动该组件易于使用,并且可以可逆地访问芯片中的滤波器和单元,以便进行下游分析。
微流控芯片有三种配置:
a)带两个连接器芯片的过滤器集成,用于跨接应用,如死端过滤或跨接灌注。
b)带有三个连接器芯片的过滤器集成,用于反式或顺式贴片应用,如死端过滤、横流过滤等。
c)带有四个连接器芯片的过滤器集成,用于反式或顺式贴片应用,如死端过滤、横流过滤或气液界面细胞培养等。
当过滤器或补片放置在两个板之间时,四对磁铁之间的力确保在8千帕的压力下自动装配。后,标准的Luer连接器的上板允许一个容易的灌注。
为确保高流量压力(高达100千帕)下良好的密封性,芯片可放置在手动螺纹夹具中进行组装和快速操作。在动态流动条件下的实验结束时,可以通过拆开夹钳和微流控芯片来轻松移除过滤器或补片。可以按照此链接订购夹钳!
好处
模块化芯片的可逆补丁集成
用芯片模制的无泄漏Luer接头
高抗光透明材料
标准显微镜玻片尺寸
组装三个组件以创建完整的微流控平台:
微流控芯片
夹紧
微滤器
滤光片集成微流控芯片
These modular microfluidic chips were designed for reversible integration of various types of filters and culture patches (to be ordered separately). The setup consists in two plastic plates in PC (Polycarbonate), each having four integrated magnets for reversible assembly and an elastomeric PDMS thin film to ensure good sealing. The Luer Connectors in the upper part of the chip allow liquid perfusion and dynamic flow conditions during your experiments. The assembly is easy to use and with a reversible access to filter and cells in chip for downstream analysis.
The microfluidic chip is available in three configurations:
a) Filter integration with tow connectors chip for trans- patch application, such as dead-end filtration or trans patch perfusion.
b) Filter integration with three connectors chip for trans- or cis- patch application, such as dead-end filtration, cross-flow filtration, etc.
c) Filter integration with four connectors chip for trans- or cis- patch application, such as dead-end filtration, cross-flow filtration, or air/liquid-liquid interface cell culture, etc.
When a filter or patch is placed between the two plates, the force between the four pairs of magnets ensures auto-assembling at pressures up to 8 kPa. Finally, the standard Luer Connectors of the upper plate allow an easy perfusion.
To ensure good sealing with high flow pressures (up to 100 kPa), the chip can be placed in a hand screwed clamp for assembling and fast operation. At the end of your experiment in dynamic flow conditions, the filter or patch can be easily removed by dissembling the clamps and the microfluidic chip. A clamp can be ordered by following this link!
Benefits
- Reversible patch integration thanks to the modular chip
- Leak-free Luer Connection molded with the chip
- Highly-resistant and optically clear material
- Standard microscope glass slide size
Assemble the three components to create a complete microfluidic platform:
- Microfluidic chip
- Clamp
- Microfilter