FMP micropatterning

FMP micropatterning 4Dcell微模式技术支持2D单元格几何形状控制。在玻璃底部设置一组图案以接收单元格。使用一种抗粘剂和一些ECM蛋白，如纤维连接蛋白或胶原蛋白，细胞可以附着在微模式施加的形状。单元格将接受这个新环境的几何形状。细胞标准化:器官生理学活器官细胞的规律性生理与其空间和机械组织密切相关。FMPsTM提供了简单和具有代表性的模型，突出了特定机构的读出。例如，FMPsTM微模式诱导心肌细胞纹状，导致心肌细胞的标准化搏动特性和内部组织。

4Dcell微图案多孔板具有组织良好的培养基质，可实现细胞的归一化。细胞均匀分布在胶粘剂上，具有可控的几何形状，可使检测标准化。FMP micropatterning

4Dcell micropatterned multi-well plates hold a perfectly organized culture substrate aiming for cell normalization. Evenly distributed on adhesive patterns, cells have a controlled geometry allowing a standardization of the assays.

The 4Dcell micropatterning technology enables a 2D cell geometry control. A set of patterns is arranged on a glass bottom to receive cells. Using an anti adhesive agent and some ECM proteins such as fibronectin or collagen, cells can adhere to the shape imposed by the micropattern. Cells are going to embrace the geometry of this new environment.

CELL STANDARDIZATION: ORGAN PHYSIOLOGY

The regular physiology of cells in living organs is closely linked with its spatial and mechanical organization.

FMPsTM offer simple and representative models highlighting organ specific read-outs. For instance, FMPsTM Micropatterns induce striation of cardiomyocyte leading to standardized beating properties and internal organization.