flexcell SpillGuard®培养板， SpillGuard® cul

BioFlex双向拉应力培养板, Uniflex单向拉应力培养板 、TissueTrain三维细胞组织培养板等系列细胞培养一起使用,
培养板类型、包被表面材料丰富：Amino, Collagen （Type I or IV）, Elastin, ProNectin （R GD）, Laminin （YIGSR）.表面涂层丰富的
包被材料， 您可以跟根据不同细胞组织可以灵活选择不同包被材料表面

 

BioFlex双向拉应力培养板, Uniflex单向拉应力培养板 、TissueTrain三维细胞组织培养板等系列细胞培养一起使用,
培养板类型、包被表面材料丰富：Amino, Collagen (Type I or IV), Elastin, ProNectin (R GD), Laminin (YIGSR).表面涂层丰富的
包被材料， 您可以跟根据不同细胞组织可以灵活选择不同包被材料表面 （包被材料选择参考）。

该应力加载系统配套培养板	zui大伸展率
Culture Plate for tension system	Max Achievable Strain
BioFLEX®双向应力细胞培养板(BioFLEX®CULTURE PLATES)	21.80%
Tissue Train三维细胞组织培养板(Tissue Train culture plates)	20.80%
UniFlex™单向应力细胞培养板(UniFlex™Culture Plates)	12.20%
24孔高通量BIOFLEX®培养板培养板（HT BIOFLEX®CULTURE PLATES）	15.00%
No Loading Stations	33%

1、BioFLEX®双向应力细胞培养板(BioFLEX®CULTURE PLATES)

BIOFLEX®CULTURE PLATES（BIOFLEX®培养板培养板）
编号产品		产品名称
BF-3001U-Case（每箱40块）	BF-3001E-Each(每块)	BioFlex Culture Plate-Untreated（6孔表面未处理的BioFLEX®双向应力细胞培养板）
BF-3001A-Case（每箱40块）	BF-3001A-Each(每块)	BioFlex Culture Plate-Amino （6孔氨基BioFLEX®双向应力细胞培养板）
BF-3001C-Case（每箱40块）	BF-3001C-Each(每块)	BioFlex Culture Plate-Collagen Type I （6孔胶原I 型BioFLEX®双向应力细胞培养板）
BF-3001C(IV)-Case（每箱40块）	BF-3001C(IV)-Each(每块)	BioFlex Culture Plate-Collagen Type IV （6孔胶原IV型BioFLEX®双向应力细胞培养板）
BF-3001E-Case（每箱40块）	BF-3001E-Each(每块)	BioFlex Culture Plate-Elastin （6孔弹力BioFLEX®双向应力细胞培养板）
BF-3001P-Case（每箱40块）	BF-3001P-Each(每块)	BioFlex Culture Plate-ProNectin （6孔 ProNectin BioFLEX®双向应力细胞培养板）
BF-3001L-Case（每箱40块）	BF-3001L-Each(每块)	BioFlex Culture Plate-Laminin （6孔层粘连蛋白BioFLEX®双向应力细胞培养板）

2、UniFlex™单向应力细胞培养板(UniFlex™Culture Plates)

• BioFlex细胞培养板和FX-5000T应力加载系统配套使用，为细胞提供应力加载。
• 孔板底部是由弹性硅胶模制作而成，柔韧性好，透明度高。
• 6孔圆形，总生长面积57.75 cm²(9.62 cm²/孔).
• 孔板底部的硅胶模超薄，厚度仅为0.020",(0.0508cm)可以使用标准正立式显微镜/倒立显微镜观察细胞。
• 五种不同包被的培养表面：Amino, Collagen (Type I or IV), Elastin, ProNectin (R GD), Laminin (YIGSR).
  Covalently bound matrix surfaces: Amino, Collagen (Type I or IV), Elastin, Pronectin®(RGD), and Laminin (YIGSR).（包被材料选择参考）
• 光学性能佳，自身荧光低。
• 当与圆柱形加载平台共同使用时，可以对细胞进行均匀的径向和圆周应力加载。
• UniFlex细胞培养板和FX-5000T应力加载系统和TissueTrain细胞培养系统配套使用。
• 准确测量应力---负压系统曲线，保证应力的准确性和可重复性。
• 单轴向应力作用于宽0.6英寸x0.952英寸(3.68 cm²)的长方形区域中。
• 单轴向应力变幅在+/-1.5%.
• 五种不同包被的培养表面：Amino, Collagen (Type I or IV) Elastin, ProNectin (RGD), Laminin (YIGSR)
  （包被材料选择参考）
• 为获得准确的单轴向应力，必须和弧矩形应力加载平台配套使用。

  编号产品		产品名称
  UF-4001U-Case（每箱40块）	UF-4001U-Each(每块)	UniFlex Culture Plate-Untreated（6孔表面未处理的BioFLEX®双向应力细胞培养板）
  UF-4001A-Case（每箱40块）	UF-4001A-Each(每块)	UniFlex Culture Plate-Amino（6孔氨基UniFlex™单向应力细胞培养板）
  UF-4001C-Case（每箱40块）	UF-4001C-Each(每块)	UniFlex Culture Plate-Collagen Type I（6孔胶原I 型UniFlex™单向应力细胞培养板）
  UF-4001C(IV)-Case（每箱40块）	UF-4001C(IV)-Each(每块)	UniFlex Culture Plate-Collagen Type IV（6孔胶原IV型UniFlex™单向应力细胞培养板）
  UF-4001E-Case（每箱40块）	UF-4001E-Each(每块)	UniFlex Culture Plate-Elastin （6孔弹力UniFlex™单向应力细胞培养板）
  UF-4001P-Case（每箱40块）	UF-4001P-Each(每块)	UniFlex Culture Plate-ProNectin （6孔ProNectin UniFlex™单向应力细胞培养板）
  UF-4001L-Case（每箱40块）	UF-4001L-Each(每块)	UniFlex Culture Plate-Laminin （6孔层粘连蛋白UniFlex™单向应力细胞培养板）
  3、HT BIOFLEX®CULTURE PLATES（高通量BIOFLEX®培养板培养板）
  白色板
  编号产品		产品名称
  HTPW-3001U-Case（每箱40块）	HTPW-3001U-Each(每块)	White HT BioFlex Culture Plate-Untreated（白色24孔高通量表面未处理培养板）
  HTPW-3001A-Case（每箱40块）	HTPW-3001A-Each(每块)	White HT BioFlex Culture Plate-Amino（白色24孔高通量氨基培养板）
  HTPW-3001C-Case（每箱40块）	HTPW-3001C-Each(每块)	White HT BioFlex Culture Plate-Collagen Type I（白色24孔高通量胶原I型培养板）
  HTPW-3001C(IV)-Case（每箱40块）	HTPW-3001C(IV)-Each(每块)	White HT BioFlex Culture Plate-Collagen Type IV（白色24孔高通量胶原IV型培养板）
  HTPW-3001E-Case（每箱40块）	HTPW-3001E-Each(每块)	White HT BioFlex Culture Plate-Elastin（白色24孔高通量弹力培养板）
  HTPW-3001P-Case（每箱40块）	HTPW-3001P-Each(每块)	White HT BioFlex Culture Plate-ProNectin（白色24孔高通量ProNectin 培养板）
  HTPW-3001L-Case（每箱40块）	HTPW-3001L-Each(每块)	White HT BioFlex Culture Plate-Laminin（白色24孔高通量层粘连蛋白培养板）
  黑色板
  HTPB-3001U-Case（每箱40块）	HTPB-3001U-Each(每块)	Black HT BioFlex Culture Plate-Untreated（黑色24孔高通量表面未处理培养板）
  HTPB-3001A-Case（每箱40块）	HTPB-3001A-Each(每块)	Black HT BioFlex Culture Plate-Amino（黑色24孔高通量氨基培养板）
  HTPB-3001C-Case（每箱40块）	HTPB-3001C-Each(每块)	Black HT BioFlex Culture Plate-Collagen Type I（黑色24孔高通量胶原I培养板）
  HTPB-3001C(IV)-Case（每箱40块）	HTPB-3001C(IV)-Each(每块)	Black HT BioFlex Culture Plate-Collagen Type IV（黑色24孔高通量胶原IV培养板）
  HTPB-3001E-Case（每箱40块）	HTPB-3001E-Each(每块)	Black HT BioFlex Culture Plate-Elastin（黑色24孔高通量弹力培养板）
  HTPB-3001P-Case（每箱40块）	HTPB-3001P-Each(每块)	Black HT BioFlex Culture Plate-ProNectin（黑色24孔高通量ProNectin培养板）
  HTPB-3001L-Case（每箱40块）	HTPB-3001L-Each(每块)	Black HT BioFlex Culture Plate-Laminin（黑色24孔高通量层粘连蛋白培养板）

  该FX-5000T系统增配的三维培养功能模块后三维细胞组织培养配套耗材

  CIRCULAR FOAM TISSUE TRAIN CULTURE PLATES （圆形三维细胞组织培养板采用弹性底部，可用来制备三维基质蛋白细胞培养物，并提供双轴向拉力，不需要生物胶槽(Trough Loader)）
  编号产品		产品名称
  TTCF-4001U-Case	TTCF-4001U-Each	Circular Foam Culture Plate-Untreated
  TTCF-4001A-Case	TTCF-4001A-Each	Circular Foam Culture Plate-Amino
  TTCF-4001C-Case	TTCF-4001C-Each	Circular Foam Culture Plate-Collagen Type I
  TTCF-4001C(IV)-Case	TTCF-4001C(IV)-Each	Circular Foam Culture Plate-Collagen Type IV
  TTCF-4001E-Case	TTCF-4001E-Each	Circular Foam Culture Plate-Elastin
  TTCF-4001P-Case	TTCF-4001P-Each	Circular Foam Culture Plate-ProNectin
  TTCF-4001L-Case	TTCF-4001L-Each	Circular Foam Culture Plate-Laminin
  TISSUE TRAIN CULTURE PLATES （三维细胞组织培养板采用弹性底部，可用来制备三维基质蛋白细胞培养物，并提供单轴向拉力。）
  编号产品		产品名称
  Foruse with Standard Trough Loaders (与线形生物胶槽配套使用)
  TT-4001U-Case	TT-4001U-Each	Tissue Train Culture Plate-Untreated
  TT-4001A-Case	TT-4001A-Each	Tissue Train Culture Plate-Amino
  TT-4001C-Case	TT-4001C-Each	Tissue Train Culture Plate-Collagen Type I
  TT-4001C(IV)-Case	TT-4001C(IV)-Each	Tissue Train Culture Plate-Collagen Type IV
  TT-4001E-Case	TT-4001E-Each	Tissue Train Culture Plate-Elastin
  TT-4001P-Case	TT-4001P-Each	Tissue Train Culture Plate-ProNectin
  TT-4001L-Case	TT-4001L-Each	Tissue Train Culture Plate-Laminin
  Foruse with Trapezoidal Trough Loaders (与梯形生物胶槽配套使用)
  编号产品		产品名称
  TTTP-4001U-Case	TTTP-4001U-Each	Trapezoidal TT Culture Plate-Untreated
  TTTP-4001A-Case	TTTP-4001A-Each	Trapezoidal TT Culture Plate-Amino
  TTTP-4001C-Case	TTTP-4001C-Each	Trapezoidal TT Culture Plate-Collagen Type I
  TTTP-4001C(IV)-Case	TTTP-4001C(IV)-Each	Trapezoidal TT Culture Plate-Collagen Type IV
  TTTP-4001E-Case	TTTP-4001E-Each	Trapezoidal TT Culture Plate-Elastin
  TTTP-4001P-Case	TTTP-4001P-Each	Trapezoidal TT Culture Plate-ProNectin
  TTTP-4001L-Case	TTTP-4001L-Each	Trapezoidal TT Culture Plate-Laminin

  该FX-5000T系统增配的压应力加载功能模块后三维细胞组织压力培养配套耗材

  CIRCULAR FOAM TISSUE TRAIN CULTURE PLATES （圆形三维细胞组织培养板采用弹性底部，可用来制备三维基质蛋白细胞培养物，并提供双轴向拉力，不需要生物胶槽(Trough Loader)）
  编号产品		产品名称
  TTCF-4001U-Case	TTCF-4001U-Each	Circular Foam Culture Plate-Untreated

 

BioFlex® Culture Plate  Catalog Page   | Product Information | Brochure | Application Page

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Flexible-bottomed culture plate that works with the Flexcell® FX-5000™ Tension Systemto provide a mechanical load regimen to cells in monolayer (see Fig. 1 below). 6-well culture plate with total growth surface area of 57.75 cm2. Rubber membranes are optically clear for direct viewing of cells with an inverted or upright microscope. Covalently bound matrix surfaces: Amino, Collagen (Type I or IV), Elastin, Pronectin® (RGD), and Laminin (YIGSR). Learn more in Tech Report 106: Matrix Bonded Growth Surfaces. Growing Cells in a More Natural Matrix Environment. Available individually or by the case of 40* plates. *5% Savings (based on buying 40 plates at the individual price) Applications of BioFlex® Culture Plates Mechanical Load - use with the FX-5000™ Tension System to research the effects of equibiaxial tensile strain on cells in monolayer culture. Softer Substrate - provides a softer substrate for cell growth (when compared to standard plastic culture dishes) which better mimics in situ conditions for some cell types like trabecular meshwork cells (see Aga et al. Invest Ophthalmol Vis Sci 55(9):5497-509, 2014). Matrix Coated Surface - culture plate surfaces are coated with various matrix proteins, such as type I collagen and laminin, to better simulate in vivo conditions (see Tech Report 106: Matrix Bonded Growth Surfaces. Growing Cells in a More Natural Matrix Environment). Traumatic Injury - can be used in studies looking at traumatic injury in astrocytes and neurons, where the injury is produced with a Cell Injury Controller that controls a burst of gas which deforms the BioFlex® membrane creating large biaxial strains (see Ellis et al. J Neurotrauma 12 325–339, 1995; Ahmed et al. J Neurochem 74(5):1951-1960, 2000; Augustine et al. Neuroscience 274:1-10, 2014). Read more about Applying Mechanical Load to Cells in Monolayer Culture   Figure 1: Equibiaxial strain application (with a FX-5000™ Tension System) to cells plated in the well of a BioFlex® culture plate. Relevant Tech Reports & Other Information 101: Loading Stations™. Quantification of Strain on the Membrane Surface 106: Matrix Bonded Growth Surfaces. Growing Cells in a More Natural Matrix Environment 202: Viewing Cells on Flexcell®'s Culture Plates. Light and Electron Microscope Techniques and Immunofluorescent Imaging    BioFlex® Culture Plates Product Information 6-Well Equibiaxial Loading Stations™ Product Information FlexStop™ Product Information Flexcell® Transwell Holder Product Information    Culture Plate & Loading Station™ User's Manual Flexcell® FX-5000™ Tension System User Manual

 

 

The History of Flexcell^®
In 1978, Albert J. Banes, Ph.D., an Assistant Professor in the Surgery Department at the University of North Carolina at Chapel Hill, received his first small grant for devising a method to apply regulated strain to cultured cells. He built prototypes of the current Flexcell^® Tension System in the shop using only a timer, a simple solenoid valve to control pressure in on/off modes, and a needle valve to regulate the magnitude of the pressure. He built a baseplate with vacuum channels in Plexiglas and used natural gum rubber as the seal between the culture plate bottom and the vacuum chamber. Dr. Banes polymerized his own rubber membranes from medical grade Dow silastic components. A cast material that eventually proved satisfactory for the membrane in a 6-well, 35 mm diameter culture plate that had the well bottoms drilled out to receive the cast membranes. A Commodore Vic 20 was the first commercial microprocessor used to control the valves. The software program and a controller board were designed by Dr. Banes and a well grounded electronics engineer, Olivier Monbureau. A Commodore 64 was the next generation computer used, followed by a Tandy computer, then IBM clones. Today, Flexcell^® develops its own software and builds custom computers and controller boards and assembles them at its plant in Burlington, NC.

Dr. Banes' inlectual property was awarded the first patent in the field of Cytomechanics. He believed that this technology could become important scientifically as well as medically if a market driver could be found. In his first patent describing the technology, he included the thought that cyclically stretching cells and tissues could lead to adaptation of cells to a mechanically active environment such as dermal fibroblasts cultured in vitro in a skin construct. Along with his father in Pennsylvania, G.B. Banes, J.D., they created Flexcell^® Inc. The company's mission was to commercialize the technology to make it available to all scientists as well as find medically relevant uses. His first full publication (Journal of Cell Science, 1985) in the area demonstrated the utility of the system and that cyclic strain altered the expression of cytoplasmic filament proteins such as actin and tubulin in tendon cells.

Continued development of the technologies behind the Flexcell^® Tension and Compression Systems has taken much of Dr. Banes' time. Dr. Banes became the first university professor to be permitted to retain his academic professorship and be president of a company (Flexcell^® International Corporation) by a decision of the Committee on Industrial Faculty Relations at the University of North Carolina at Chapel Hill.

Dr. Banes holds three patents on the basic cell stretching technology and several more on other technologies including a DNA transfection technique using flexation of cells and a spill resistant culture plate called the SpillGuard^® culture plate. He continues to develop new products for cell culture and cell stretching as well as submit patents assigned to Flexcell^® International Corporation.
 

 

Our Mission

• To be an industry leading developer and manufacturer of biotechnology products for cellular and tissue biomechanics research.
• To provide innovative products and solutions to researchers enabling the advancement of molecular biology and tissue engineering research.
• To be a valued business partner to both our suppliers and distributors and honorable employer to our workforce while maintaining a profitable operation.