Z03367 TRAIL, Mouse
| 参考价 | ￥534.00 |
具体成交价以合同协议为准
- 公司名称 漠宝（厦门）生物科技有限公司
- 品牌GenScript/金斯瑞
- 型号Z03367
- 所在地厦门市
- 厂商性质代理商
- 更新时间2025/5/22 8:56:51
- 访问次数 16
规格
| 50 μg | 534.00元 | 14 件可售 |
联系方式：高智星15860722185 查看联系方式
联系我们时请说明是化工仪器网上看到的信息，谢谢!
9min快速湿转仪，10min蛋白染色仪，全自动WB系统，预制胶，WB试剂，Protein A/Ni-NTA/Glutathione/Anti-His/Anti-flag Resin，磁珠，ECL发光试剂，血清，细胞，培养基，凋亡检测试剂盒，细胞活力or增殖检测试剂盒，细胞荧光染料，抗体，ELISA试剂盒，重组蛋白，真正无毒核酸染料，琼脂糖，qPCR Mix，RT-PCR mix，质粒，外泌体解决方案，CRISPR/Cas9试剂等
| 供货周期 | 现货 | 规格 | 50 μg |
|---|---|---|---|
| 货号 | Z03367 | 应用领域 | 医疗卫生,食品/农产品,化工,生物产业,制药/生物制药 |
TNF-related apoptosis-inducing ligand (TRAIL), also known as Tumor Necrosis Factor Super-Family 10 (TNFSF10) or apoptosis 2 ligand (Apo2L), is a pleiotropic cytokine thatbelongs to the TNF superfamily.
产品简介
| Species | Mouse | |
| Protein Construction | Expressed with an N-terminal Gly.
| |
| Purity | > 98% as analyzed by SDS-PAGE | |
| Endotoxin Level | < 0.2 EU/μg of protein by gel clotting method | |
| Biological Activity | ED50 < 100.0 ng/ml, measured by the cell growth inhibitory assay using RPMI-8226 cells, corresponding to a specific activity of > 1.0 × 104 units/mg. | |
| Expression System | E. coli | |
| Apparent Molecular Weight | ~20 kDa, on SDS-PAGE under reducing conditions. | |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. | |
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. | |
| Storage & Stability | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
图例
技术背景
| Target Background | TNF-related apoptosis-inducing ligand (TRAIL), also known as Tumor Necrosis Factor Super-Family 10 (TNFSF10) or apoptosis 2 ligand (Apo2L), is a pleiotropic cytokine thatbelongs to the TNF superfamily. Full length TRAIL expressed in vivo is a type II transmembrane protein, although the soluble form also exists and functions. TRAIL has four major receptors: two death receptors DR4 and DR5, and two decoy receptors DcR1 and DcR2. TRAIL binds to the death receptors which recruits the FAS-associated death domain and activates caspases 8 and 10 which eventually leads to apoptosis. Because of its antitumor potential, TRAIL is activelystudied as a therapeutic agent. On the other hand, abnormal expression of TRAIL in small arteries can induce the proliferation of smooth muscle cells, thereby increasing vascular remodeling and pulmonary arterial hypertension. |
| Synonyms | Tumor necrosis factor ligand superfamily member 10; TNF-related apoptosis-inducing ligand; Protein TRAIL; CD_antigen: CD253; Tnfsf10 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
采购中心
化工仪器网