91605ES 重组人血小板衍生生长因子BB
参考价 | ¥535.00-¥17385.00 |
- 公司名称 翌圣生物科技(上海)股份有限公司
- 品牌Yeasen/翌圣生物
- 型号91605ES
- 所在地上海市
- 厂商性质生产厂家
- 更新时间2024/5/6 10:38:20
- 访问次数 69
2μg | 535.00元 | 99 件可售 |
10 μg | 1855.00元 | 99 件可售 |
50 μg | 4635.00元 | 99 件可售 |
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供货周期 | 现货 | 应用领域 | 医疗卫生,生物产业 |
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Product Description
Platelet-derived growth factor (PDGF) was discovered as a major mitogenic factor present in serum but absent from plasma. In vitro, PDGF-BB stimulated MAP kinase activity and cell motility of isolated lymphatic endothelial cells. In vivo, PDGF-BB potently induced growth of lymphatic vessels. Expression of PDGF-BB in murine fibrosarcoma cells induced tumor lymphangiogenesis, leading to enhanced metastasis in lymph nodes. The PDGF signaling system contributes to and vascular remodeling. Growth factors such as PDGF exert potent effects on wound healing including the regeneration of tooth-supporting structures.
Product Properties
Synonyms | Becaplermin, ODGF, PDGF-2, PDGFBB, PDGF-BB |
Accession | P01127 |
GeneID | 5155 |
Source | E.coli-derived human PDGF-BB protein, Ser82-Thr190, with an N-terminal Met. |
Molecular Weight | Approximately 24.8 kDa |
AA Sequence | MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT |
Tag | None |
Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
Purity | > 97 % by SDS-PAGE and HPLC analyses. |
Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 3 ng/ml, corresponding to a specific activity of > 3.3 × 105 IU/mg. |
Endotoxin | < 1.0 EU per 1μg of the protein by the LAL method. |
Formulation | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ for 1 year.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 °C under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
For your safety and health, please wear lab coats and disposable gloves for operation.
For research use only.
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