CBP71391 CB1/β-Arrestin/CHO GPCR细胞
具体成交价以合同协议为准
- 公司名称 南京科佰生物科技有限公司
- 品牌 cobioer/科佰生物
- 型号 CBP71391
- 产地
- 厂商性质 代理商
- 更新时间 2023/3/28 10:40:44
- 访问次数 466
产品标签
联系方式:蒋经理18066071954 查看联系方式
联系我们时请说明是化工仪器网上看到的信息,谢谢!
供货周期 | 现货 | 规格 | T-25 Flask |
---|---|---|---|
货号 | CBP71391 | 应用领域 | 生物产业 |
CBP71391 | |
I. Background | |
The cannabinoid receptor CNR1 is Gs-coupled GPCRs expressed in primarily CNS and some peripheral neurones; particularly prevalent in basal ganglia, hippocampus, cerebellum, cerebral cortex and also presented in some non-neuronal cells and tissues, for example leukocytes and testis. A shorter human splice variant (411aa) has been identified in the brain and other tissues by reverse-transcriptase PCR but mRNA levels were less than 10-fold the levels of the longer isoform. The pharmacological characteristics of the isoforms are similar. | |
II. Introduction | |
Host Cell: | CHO |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12k+10%FBS+5ug/ml puromycin+5ug/ml blasticidin |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): | Functional assay for CB1 receptor |
Transducer: | Gi/Go family |
Ⅲ. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data | |
Figure 1. Recombinant CB1/β-Arrestin/CHO constitutively expressing CB1. | |
Figure 2.Dose response of CP-55940 in CB1 β-Arrestin CHO-K1 Cell Line (C2) | |
Figure 3.Inhibition of CP-55940-induced Beta-Arrestin Recruitment in CB1 Beta-Arrestin CHO-K1 Cells (C2). |