CBP10239 BRAF p.G466V Reference Standard 标准品
| 参考价 | ¥ 900 |
| 订货量 | ≥1件 |
具体成交价以合同协议为准
- 公司名称 南京科佰生物科技有限公司
- 品牌 cobioer/科佰生物
- 型号 CBP10239
- 产地
- 厂商性质 代理商
- 更新时间 2022/11/25 15:12:20
- 访问次数 365
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| 供货周期 | 现货 | 规格 | 1ug |
|---|---|---|---|
| 货号 | CBP10239 | 应用领域 | 生物产业 |
CBP10239 | |
| Format | Genomic DNA |
| Description | BRAF G466V lies within the protein kinase domain of the Braf protein (UniProt.org). G466V results in impaired Braf kinase activity, but paradoxically activates MEK and ERK through transactivation of CRAF in cell culture (PMID: 22649091, PMID: 28783719), and in one of two cell lines, G466V decreased cell proliferation and cell viability as compared to wild-type Braf (PMID: 29533785). |
| Technical Data | |
| DNA Change | c.1397G>T |
| AA Change | p.G466V |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | ENST00000288602 |
| Cosmic ID | COSM451 |
| Chr position(GRCh37) | chr7:140481411 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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