美国NovaBios 甲型/乙型/甲流H1N1三通道核酸诊断试剂

甲型/乙型/甲流H1N1三通道核酸诊断试剂

广州健仑生物科技有限公司

广州健仑长期供应各种流感检测试剂，包括进口和国产的品牌，主要包括日本富士瑞必欧、日本生研、美国BD、美国NovaBios、美国binaxNOW、凯必利、广州创仑等主流品牌。

甲型/乙型/甲流H1N1三通道核酸诊断试剂

1、甲/乙型流感病毒如何划分的？
流感病毒长成这个样子：外面是包膜，里面是核心，表面和里面有一些可供辨识的结构（主要是蛋白/糖蛋白），根据这些在RNA中是否表达来给它们分型和分亚型。RNA可以分成数个片段。
甲乙丙的核心基本结构都是一样的，有核蛋白（对应1个片段）和RNA多聚酶（图中的P蛋白）（对应3个片段）。
甲和乙表面有2种刺突（图中的血凝素和神经氨酸酶）（对应2个片段）
甲和乙的区别在于：甲在包膜上和包膜内有2种膜蛋白（对应2个片段），而乙则是有2种non-structure蛋白（对应2个片段）。所以甲和乙的RNA都是有8个片段。
丙只有1种刺突（血凝素），所以它的RNA有7个片段。
再往下分，还可以分亚型。比如这次的禽流感病毒H7N9，指的是血凝素属于已发现的第7种、神经氨酸酶属于已发现的第9种。
2、抗原检测阴/阳性具有什么含义？抗体检测呢？
免疫系统始终在监视着人体内的状况。病原菌进入人体后，经过免疫系统的处理，那些“可供辨识的结构”们就有可能被识别出来，免疫系统发现这货不是人体正常有的，于是根据这些被识别的标记展开反病原菌行动。被辨识的就是抗原。

1, A / B influenza virus how to divide?
The flu virus grows like this: the envelope is enveloped outside, the core is inside, there are some recognizable structures (mainly protein / glycoproteins) on the surface and inside, and they are classified and sub-divided according to whether they are expressed in RNA type. RNA can be divided into several fragments.
The basic structure of A and B core are the same, there are nuclear protein (corresponding to a fragment) and RNA polymerase (P protein in the figure) (corresponding to three fragments).
There are two kinds of spikes on the surface of A and B (hemagglutinin and neuraminidase in the figure) (corresponding to two fragments)
The difference between A and B is that A has two membrane proteins (corresponding to two fragments) on the envelope and in the envelope, while B has two non-structure proteins (corresponding to two fragments). So A and B RNA is 8 fragments.
C has only one spike (hemagglutinin), so its RNA has seven fragments.
Further points down, you can sub-sub-type. For example, the H7N9 bird flu virus, which refers to the hemagglutinin has been found in the first 7, neuraminidase belongs to the 9th found.
2, antigens detection of negative / positive What is the meaning? Antibody detection?
The immune system is always monitoring the condition in the body. After the pathogen enters the human body and is processed by the immune system, those "structures for identification" are likely to be identified. The immune system finds that the product is not normally available to the human body. Therefore, anti-pathogenic bacteria are activated according to these identified markers. Identified is the antigen.

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【公司名称】 广州健仑生物科技有限公司
【市场部】    杨永汉

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【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

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One of the essential features of anchorage-dependent cells in cell culture is the ability and need to attach to the surface of the object for growth. Cells make themselves in contact with the solid support and sequester by secreting some of the extracellular matrix. On Earth, cells are usually adhered to the solid surface by contact as they sink to the bottom of the flask and onto the microcarriers. The STS-8 space flight test confirmed that the secretion of the cell membrane and adherent proteins in space was normal and that human renal cells were attached to the beads more effectively in the microgravity environment than the ground controls, thus transporting the cells to space Freezing and other methods of immobilization are feasible when needed. This is of paramount importance for the long-term exploration of space in the future and for the basic research in biology at the space station, as well as the commercial development of biotechnology.
Microencapsulation is a method of fixing cells, which is a composite droplet of alginate surrounded by a semipermeable polymer layer. The polymer, which is porous, allows fluid to move in and out freely, but also protects the cells and reduces the damaging effects of shear forces in bioreactors due to such factors as drastic changes in gravity at launch and return.
In mammalian cell preservation studies, it has been reported that biologically active cells are preserved in subcooling-in-oil technology for future research on the ISS. Dry blood cells used in aerospace trials save the method, to avoid the use of refrigerators and other refrigeration equipment. The standard method of collecting astronauts' blood samples is by gel separation in a vacuum tube (filtration of liquid components, retention of cell components). The chemical properties of the sample can be better preserved by collecting and preserving it under microgravity, such as 80% of the commonly used analytes can be stored without electrolytes for several months.