JAZF1抗体JAZF1

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JAZF1抗体JAZF1主要参数>>>

中文名称：  JAZF1抗体
英文名称：  JAZF1
抗体别名：  JAZF zinc finger 1; JAZF1; JAZF1_HUMAN; Juxtaposed with another zinc finger protein 1; TAK1 interacting protein 27; TAK1-interacting protein 27; TIP27; Zinc finger protein 802; ZNF802.
抗体来源：  Rabbit
克隆类型：  Polyclonal
交叉反应：  Human，Mouse，Rat，Chicken，Pig，Horse，Rabbit，Sheep，
产品应用：  WB=1:100-500ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500
抗体浓度：  1mg/1ml
抗体性状：  Lyophilized or Liquid
免 疫 原：   KLH conjugated synthetic peptide derived from human JAZF1
分 子 量：   27kDa
抗体亚型：  IgG
纯化方法：  affinity purified by Protein A
细胞定位：  
研究领域：  
保存方法：
0.01M TBS(pH7.4) with 1% BSA， 0.03% Proclin300 and 50% Glycerol.
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍：
background:
This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized [provided by RefSeq, Jul 2008]

Function:
Potential transcription factor.

Subunit:
Interacts with TAK1.

DISEASE:
Note=A chromosomal aberration involving JAZF1 may be a cause of endometrial stromal tumors. Translocation t(7;17)(p15;q21) with SUZ12. The translocation generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer. Translocation t(6;7)(p21;p22) with PHF1.

Similarity:
Contains 3 C2H2-type zinc fingers.

Gene ID:
221895

Database links:

Entrez Gene: 221895 Human

Entrez Gene: 231986 Mouse

Entrez Gene: 685879 Rat

Omim: 606246 Human

SwissProt: Q86VZ6 Human

SwissProt: Q80ZQ5 Mouse

SwissProt: Q5RDF5 Orangutan

Unigene: 368944 Human

Unigene: 386865 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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