肺癌肿瘤阻抑基因1抗体，SynCAM/TSLC1抗体

中文名称：肺癌肿瘤阻抑基因1抗体，SynCAM/TSLC1抗体

英文名称：Anti-SynCAM/TSLC1

货号：BYK-1147R

克隆类型：polyclonal or monoclonal

抗体来源：Rabbit or Mouse
性状：Lyophilized or Liquid
产品类型：一抗
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
标记物：可以提供抗体相对应的 HRP   Biotin  Gold   RBITC   AP   FITC   Cy3 Cy5   Cy5.5   Cy7   PE   PE-Cy3   PE-CY5   PE-CY5.5   PE-CY7   APC   Alexa Fluor 350    Alexa Fluor 488    Alexa Fluor 555     Alexa Fluor 647 等标记物抗体，详情请询！

肺癌肿瘤阻抑基因1抗体，SynCAM/TSLC1抗体 详细介绍：

Mediates homophilic cell-cell adhesion in a Ca（2+）-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca（2+）-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer （NSCLC） cells. Interaction with CRTAM promotes natural killer （NK） cell cytotoxicity and interferon-gamma （IFN-gamma） secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. May act as a synaptic cell adhesion molecule that drives synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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