磷酸化血管内皮生长因子受体2抗体,VEGFR2(Tyr951)抗体
参考价 | ¥ 1480 |
订货量 | ≥1 |
- 公司名称 上海博研Elisa试剂盒供应商
- 品牌 Abcam
- 型号
- 产地 进口/国产
- 厂商性质 生产厂家
- 更新时间 2016/7/8 8:25:20
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中文名称:磷酸化血管内皮生长因子受体2抗体,VEGFR2(Tyr951)抗体
英文名称:Anti-phospho-VEGFR2(Tyr951)
货号:BYK-2674R
克隆类型:polyclonal or monoclonal
抗体来源:Rabbit or Mouse
性状:Lyophilized or Liquid
产品类型:一抗
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
标记物:可以提供抗体相对应的 HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 等标记物抗体,详情请询!
磷酸化血管内皮生长因子受体2抗体,VEGFR2(Tyr951)抗体 详细介绍:
VEGF receptor 2 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2 and phosphotyrosine binding containing signalling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGF receptor 2 and its intrinsic tyrosine kinase activity. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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