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Source
Rabbit
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Applications
WB
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Reactivity
Human, Mouse
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Dilution
WB 1：500-2000
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Storage
-20°C/1 year
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Specificity
This antibody detects endogenous levels of C8AP2 at Human/Mouse
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Source/Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogen
Synthesized peptide derived from human C8AP2
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Uniprot No
Q9UKL3
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008],
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Other
CASP8AP2 FLASH KIAA1315 RIP25, C8AP2
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Mol.Wt (Da)
218020
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Concentration
1 mg/ml
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