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Source
Rabbit
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Applications
WB,ELISA
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Reactivity
Human
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Dilution
WB: 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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Storage
-20°C/1 year
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Specificity
CA IV Polyclonal Antibody detects endogenous levels of CA IV protein.
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Source/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
Synthesized peptide derived from the Internal region of human CA IV.
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Uniprot No
P22748
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Alternative names
CA4; Carbonic anhydrase 4; Carbonate dehydratase IV; Carbonic anhydrase IV; CA-IV
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Polyclonal
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Isotype
IgG
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Background
carbonic anhydrase 4(CA4) Homo sapiens Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. [provided by RefSeq, Jul 2008],
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Other
CA4, Carbonic anhydrase 4
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Mol.Wt (Da)
35032
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Concentration
1 mg/ml
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