双功能蛋白交联剂和生物素交联剂介绍（含结构式和英文介绍）

双功能蛋白交联剂和生物素交联剂介绍（含结构式和英文介绍）

蛋白质交联剂是一类小分子化合物，具有2个或者更多的针对特殊基团（-NH2、-COOH、-HS等）的反应性末端，可以和2个或者更多的分子分别偶联，从而使这些分子结合在一起，终形成共轭蛋白。

Protein crosslinkers are chemical compounds used to covalently bind, or conjugate, biomolecules together. In proteomics, "protein crosslinking" refers to utilizing protein crosslinkers to conjugate peptides or proteins together or to immobilize proteins to a solid support.

Protein crosslinking reagents possess reactive moieties specific to various functional groups (sulfhydryls, amines, carbohydrates, etc.) on proteins, peptides, or other molecular complexes. The atoms separating a crosslinker’s reactive groups, and eventually the conjugated proteins, form the “spacer arm”. A zero-length crosslinker refers to protein crosslinkers that join two molecules without adding additional spacer arm atoms. Homobifunctional crosslinkers have the same reactive group on both ends of the spacer arm (i.e., Amine Reactive-Amine Reactive); while heterobifunctional crosslinkers have different reactive groups on each end of a spacer arm (i.e., Sulfhydryl Reactive-Amine Reactive).

西安凯新生物科技有限公司可以提供一系列的蛋白交联剂，包含有同端双功能交联剂，异端双功能交联剂，氘代交联剂，生物素交联剂及其他种类交联剂等等产品。我们提供的交联剂产品小包装是100毫克，价格便宜，品质较好深受广大科研客户欢迎。

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Zero-Length Crosslinkers零长度交联剂：

产品名称：Sulfo-NHS

产品简介：N-hydroxysulfosuccinimide (Sulfo-NHS) is used in conjunction with EDC-HCl (EDAC-HCl) to convert carboxyl groups to Sulfo-NHS esters which react amines. Sulfo-NHS is used as a catalyst for EDC-HCl coupling and greatly increases the efficiency of the reaction.

结构式：

分子量: 217.1

CAS #: 106627-54-7

Alternative Name: Hydroxy-2,5-dioxoyrrolidine-3-sulfonate

Homobifunctional Crosslinkers 同端双功能交联剂：

产品名称：BS3

产品介绍：BS3 crosslinker (Bis[sulfosuccinimidyl] suberate; BS3) is a water soluble homobifunctional pro-tein crosslinker. The 8-atom spacer arm of the BS3 crosslinking reagent is non-cleavable and the molecule is not cell membrane permeable. The BS3 protein crosslinker possesses amino reactive Sulfo-NHS esters on both ends of the molecule and can be used to prepare antibody-protein con-jugates or for crosslinking cell surface proteins.

结构式：

分子量：572 Da

CAS #: 82436-77-9

Spacer Length: 11.4 Å

Alternative Names: Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester); BS3; Sulfo-DSS

产品名称：BS2G

简介：BS2G crosslinker (Bis[Sulfosuccinimidyl] glutarate) is a water soluble homobifunctional protein crosslinker. The BS2G protein crosslinker's 5-atom (7.7 angstrom) spacer arm is non-cleavable and the molecule is not cell membrane permeable. The BS2G crosslinking reagent's Sulfo-NHS esters are amino reactive and can be used to label cell surface proteins.

结构式：

Molecular Weight: 530.4

Spacer Length: 7.7 Å

Alternative Names: Glutaric acid bis (3-sulfo-N-hydroxysuccinimide ester); Sulfo-DSG

产品名称：BSG

简介：DSG crosslinker (Disuccinimidyl glutarate) is a homobifunctional crosslinking reagent that is membrane permeable. DSG crosslinking takes place through amine-reactive NHS esters at both ends of a 5-atom (7.7 angstrom) spacer arm. DSG must be dissolved in an organic solvent, such as DMSO or DMF, then added to an aqueous crosslinking reaction.

结构式：

Molecular Weight: 326.3

CAS #: 79642-50-5

Spacer Length: 7.7 Å

Alternative Name: Di(N-succinimidyl) glutarate

产品名称：DSP

简介：Dithiobis(succinimidyl propionate) (DSP) is a homobifunctional crosslinker that is cell membrane permeable. DSP has amine-reactive N-hydroxysuccimide (NHS) esters at both ends of a cleava-ble, 8-atom (12.0 angstrom) spacer arm. DSP contains a reducible disulfide bond in the spacer arm that make it a good choice for various applications.

结构式：

Molecular Weight: 404.4

CAS #: 57757-57-0

Spacer Length: 12.0 Å

Alternative Names: 3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester);

产品名称：DSS

简介：DSS crosslinker (Disuccinimidyl suberate) is a homobifunctional crosslinker that is cell membrane permeable. DSS has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm. The DSS crosslinking reagent must be dissolved in an or-ganic solvent, such as DMSO or DMF, then added to an aqueous crosslinking reaction.

结构式：

Molecular Weight: 368.4

CAS #: 68528-80-3

Spacer Length: 11.4 Å

Alternative Name: Suberic acid bis(N-hydroxysuccinimide)

产品名称：DTSSP

简介：DTSSP crosslinker (3,3´-Dithiobis[sulfosuccinimidylpropionate]) is a homobifunctional protein crosslinker that is cell membrane impermeable. DTSSP crosslinking reagent has primary amine-reactive N-hydroxysulfosuccinimide (Sulfo-NHS) esters at both ends of a cleavable, 8-atom (12.0 angstrom) spacer arm. DTSSP contains a reducible disulfide (thiol) bond in the spacer arm that make it a good choice for various applications.

结构式：

Molecular Weight: 608.5

CAS #: 81069-02-5

Spacer Length: 12.0 Å

产品名称：EGS

简介：EGS crosslinker, Ethylene glycolbis(succinimidylsuccinate), is a water insoluble homobifunction-al crosslinker. The 12-atom spacer arm of the EGS crosslinking reagent is cleavable. The EGS spacer arm is cleaved by hydroxylamine at pH 8.5 for 3-6 hours at 37°C. The EGS protein cross-linker possesses amino reactive NHS esters on both ends of the molecule and can be used to label intracellular proteins, since the molecule is cell membrane permeable.

结构式：

Molecular Weight: 456.36

CAS #: 70539-42-3

Spacer Length: 16.1 Å

产品名称：Sulfo-EGS

简介：Sulfo-EGS crosslinker, Ethylene glycolbis(sulfosuccinimidylsuccinate), is a water soluble homo-bifunctional crosslinker. The 12-atom spacer arm of Sulfo-EGS crosslinking reagent is cleavable. Sulfo-EGS spacer arm is cleaved by hydroxylamine at pH 8.5 for 3-6 hours at 37°C. The Sulfo-EGS protein crosslinker possesses amino reactive Sulfo-NHS esters on both ends of the molecule and can be used to label cell surface proteins, since the molecule is not cell membrane permeable.

结构式：

Molecular Weight: 660.45

Spacer Length: 16.1 Å

Alternative Names: Ethylene glycol bis (sulfosuccinimidylsuccinate);

产品名称：DSSeb

简介：DSSeb (Disuccinimidyl sebacateis membrane permeable. DSSeb crosslinks via amine-reactive NHS esters at both ends of a 10-atom (14.1 Å ) spacer arm and must dissolved in an organic sol-vent, such as DMSO or DMF, then added to an aqueous crosslinking reaction.

结构式：

Molecular Weight: 396.39

CAS # 23024-29-5

Spacer Length: 14.1 Å

Alternative Names: Sebacic acid bis(N-hydroxysuccinimide ester);

Heterobifunctional Crosslinkers异端双功能交联剂：

产品名称：BMPS

简介：BMPS is a non-cleavable, water insoluble, heterobifunctional protein crosslinker that is common-ly used to crosslink haptens to carrier proteins and enzymes to antibody. The BMPS crosslinker's spacer arm length of 5.9 angstroms is the shortest of the C3 homolog of aliphatic spacer series (see also EMCS and GMBS). The BMPS crosslinking reagent's NHS ester and maleimide reac-tive groups react with amino and sulfhydryl moites, respectively.

结构式：

Molecular Weight: 266.2

CAS #: 55750-62-4

Spacer Length: 5.9 Å

Alternative Names: N-(beta-Maleimidopropyloxy)succinimide ester

产品名称：EMCS

简介：N-(e-Maleimidocaproyloxy)succinimide ester (EMCS) is a non-cleavable, water insoluble, hetero-bifunctional crosslinker that is commonly used to crosslink haptens to carrier proteins and en-zyme to antibody. The EMCS crosslinker spacer arm is longer than GMBS. The EMCS NHS es-ter and maleimide reactive groups react with amino and sulfhydryl moieties, respectively.

结构式：

Molecular Weight: 308.3

CAS #: 55750-63-5

Spacer Length: 9.4 Å

Alternative Names: N-(epsilon-Malaimidocaproyloxy) succinimide

产品名称：GMBS

简介：GMBS is a non-cleavable heterobifunctional protein crosslinker. The GMBS crosslinking reagent is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The GMBS has a spacer arm length of 7.3 angstroms and is less immunogenic than the crosslinking analog MBS. The GMBS crosslinking reagent's NHS ester and maleimide reactive groups react with amino and sulfhydryl moites, respectively.

结构式：

Molecular Weight: 280.2

CAS #: 80307-12-6

Spacer Length: 7.3 Å

Alternative Name: 4-Maleimdobutyric acid N-succinimidyl ester

产品名称：LC-SPDP

简介：LC-SPDP crosslinker is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive het-erobifunctional protein crosslinker. The "long chain" LC-SPDP crosslinking reagent has a 15.7 angstrom spacer arm, compared to the 6.8 angstrom spacer arm of SPDP.

结构式：

Molecular Weight: 425.5

Spacer Length: 15.7 Å

Alternative Name: Succinimidyl-6-(3-[2-pyridyldithiol-propionamido) hexanoate

产品名称：MBS

简介：MBS crosslinker is a non-cleavable, water insoluble, heterobifunctional protein crosslinking rea-gent that is commonly used to crosslink haptens to carrier proteins and enzymes to antibody. The MBS crosslinking reagent's NHS ester and maleimide reactive groups react with amino and sulfhydryl moites, respectively.

结构式：

Molecular Weight: 314.3

CAS #: 58626-38-3

Spacer Length: 7.3 Å

产品名称：PDPH

简介：PDPH is a cleavable, heterobifunctional protein crosslinking reagent. The PDPH crosslinker's hydrazide group selectively reacts with oxidized carbohydrates (or carboxyls when used with EDC); while the pyridinyldisulfide moiety is reactive toward reduced thiols. Thus, PDPH protein crosslinker is an excellent choice for crosslinking glycoproteins and other polysaccharides.

结构式：

Molecular Weight: 229.3

Spacer Length: 9.2 Å

Alternative Name: 3-[2-Pyridyldithio]propionyl hydrazide

产品名称：SBA

简介：SBA crosslinker (N-Succinimidyl bromoacetate) is a sulfhydryl (thiol) and amino reactive hetero-bifunctional protein crosslinking reagent. SBA crosslinker is non-cleavable and is among the shortest amine and sulfhydryl reactive crosslinking reagents known with a spacer arm length of only 1.5 Angstroms.

Molecular Weight: 236.02

CAS #: 42014-51-7

Spacer Length: 1.5 Å

Alternative Names: Bromoacetic acid N-hydroxysuccinimide ester;

产品名称：SIA

简介：N-Succinimidyl iodoacetate (SIA) is a non-cleavable, heterobifunctional protein crosslinker. SIA is among the shortest amine and sulfhydryl (thiol) reactive crosslinkers known with a spacer arm length of 1.5 Angstroms.

Molecular Weight: 283.02

CAS #: 39028-27-8

Spacer Length: 1.5 Å

Alternative Names: Iodoacetic acid N-hydroxysuccinimide ester; Succinimidyl iodoacetate

产品名称：SMCC

简介：SMCC crosslinker (Succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate) is a heterobi-functional protein crosslinker with a maleimide group that is sulfhydryl (thiol; -SH) reactive and a NHS ester group that is amine reactive. The SMCC crosslinking reagent is permeable across the lipid bilayer of the cell membrane. The 9 atom spacer arm of SMCC is not cleavable.

Molecular Weight: 334.3

CAS #: 64987-85-5

Spacer Length: 8.3 Å

Alternative Names: 4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester;

产品名称：SMPB

简介：SMPB crosslinker (N-Succinimidyl 4-[4-maleimidophenyl]butyrate) is a heterobifunctional pro-tein crosslinking reagent that is reactive toward sulfhydryl and amino groups. The SMPB pro-tein crosslinker is an extended chain length analog of MBS crosslinker.

Molecular Weight: 356.3

CAS #: 79886-55-8

Spacer Length: 11.6 Å

Alternative Name: 4-(4-Maleimidophenyl)butyric acid N-hydroxysuccinimide ester

产品名称：SMPH

简介：SMPH crosslinker (Succinimidyl-6-[ß-maleimidopropionamido]hexanoate) is a water insoluble, heterobifunctional protein crosslinker with a non-cleavable spacer arm length of 14.3 angstroms. The SMPH crosslinking reagent has maleimide groups which are reactive to thiols (sufhydryls) and its NHS ester groups react with amines at pH 6.5-7.5 and 7-9, respectively

结构式：

Molecular Weight: 379.4

Alternative Name: Succinimidyl-6-[βmaleimidopropionamido] hexanoate

产品名称：SPDP

简介：SPDP crosslinker is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobi-functional protein crosslinker. The SPDP crosslinking reagent's reactive moites consist of an N-hydroxysuccinimide (NHS) ester that reacts with primary amines. On the other end of SPDP, the pyridinyldisulfide reacts with sulhydryls to yield a reversible disulfide bond.

Molecular Weight: 312.4

CAS #: 68181-17-9

Spacer Length: 6.8 Å

Alternative Name: 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester

产品名称：Sulfo-LC-SPDP

简介：Sulfo-LC-SPDP crosslinking reagent is a cleavable, water soluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker.

Sulfo-LC-SPDP crosslinker's reactive moites consist of an N-hydroxysulfosuccinimide (Sulfo-NHS) ester that reacts with primary amines. The other end of the Sulfo-LC-SPDP crosslinking molecule pyridinyldisulfide reacts with sulhydryls to yield a reversible disulfide bond.

Molecular Weight: 527.6

Spacer Length: 15.7 Å

Alternative Name: Sulfosuccinimidyl-6-(3’-[2-pyridyldithio]-propionamido) hexanoate

产品名称：Sulfo-MBS

简介：Sulfo-MBS crosslinker (m-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester) is a non-cleavable, water soluble, heterobifunctional protein crosslinking reagent that is commonly used to crosslink haptens to carri-er proteins and enzymes to antibody. The Sulfo-MBS crosslinking reagent's NHS ester and maleimide reac-tive groups react with amine and sulfhydryl moites, respectively.

Molecular Weight: 416.3

Spacer Length: 7.3 Å

Alternative Names: 3-Maleimidobenzoic acid N-hydroxysulfosuccinimide ester;

产品名称：Sulfo-SANPAH

简介：Sulfo-SANPAH crosslinker (N-Sulfosuccinimidyl-6-[4'-azido-2'-nitrophenylamino] hexanoate) is a water soluble, heterobifunctional protein crosslinker with a spacer arm length of 18.2 Å. Sul-fo-SANPAH crosslinking reagent contains an NHS ester that reacts with primary amines and a nitrophenylazide group that is photoreactive at 320-350 nm toward amino groups.

Molecular Weight: 492.4

CAS #: 102568-43-4

Spacer Length: 18.2 Å

产品名称：Sulfo-SMCC

Sulfo-SMCC crosslinker (Sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate) is a water soluble, heterobifunctional crosslinker. Sulfo-SMCC crosslinking reagent has an 8.3 angstrom non-cleavable spacer arm and its maleimide group reacts with sulfhydryls (thiols), while the Sulfo-NHS ester is reactive toward primary amines. Sulfo-SMCC can be used to pro-duce antibody-protein crosslinked conjugates or efficiently label cell surface proteins.

Molecular Weight: 436.4

CAS #: 92921-24-9

Spacer Length: 8.3 Å

Deuterated Crosslinkers氘代交联剂产品：

产品名称：BS2G-d4

BS2G-d4 deuterated crosslinker, Bis(Sulfosuccinimidyl) 2,2,4,4-glutarate-d4, is a water soluble and cell membrane impermeable crosslinking agent with 4 deuterium atoms to provide a 4 dal-ton shift by mass spectrometry analysis. Use BS2G-d4 crosslinking reagent in combination with the non-deuterated form of BS2G c1126-100mg or c1126-1gm for mass spectrometry studies.

Molecular Weight: 534.37

Spacer Length: 7.7 Å

Alternative Names: Glutaric acid-2,2,4,4-d4 bis (3-sulfo-N-hydroxysuccinimide ester) disodium salt

BS3-d4

BS3-d4 deuterated crosslinker, Bis(Sulfosuccinimidyl) 2,2,7,7-suberate-d4, is a water soluble and membrane impermeable crosslinking agent with 4 deuterium atoms to provide a 4 dalton shift by mass spectrometry. Use in combination with non-deuterated BS3 c1103-100mg or c1103-1gm for mass spectrometry studies.

Molecular Weight: 576.45

Spacer Length: 11.4 Å

Alternative Names: Suberic acid-2,2,7,7-d4 bis (3-sulfo-N-hydroxysuccinimide ester) disodium salt;

DSG-d4

DSG-d4 deuterated protein crosslinker (Bis[Succinimidyl] 2,2,4,4-glutarate-d4) is a cell mem-brane permeable crosslinking agent with 4 deuterium atoms to provide a 4 dalton shift by mass spectrometry analysis. Use the DSG-d4 heavy protein crosslinker in combination with the light, non-deuterated analog DSG (c1104).for mass spectrometry studies.

Molecular Weight: 330.28

Spacer Length: 7.7Å

Alternative Names: Glutaric acid-2,2,4,4-d4 bis (N-hydroxysuccinimide ester);

DSS-d4

DSS-d4 deuterated crosslinker (Bis[Succinimidyl] 2,2,7,7-suberate-d4) is a cell membrane perme-able crosslinking agent with 4 deuterium atoms that provide a 4 dalton shift by mass spectrome-try analysis. Use DSS-d4 heavy crosslinker in combination with DSS, the light non-deuterated analog c1105-100mg or c1105-1gm, for mass spec studies.

Molecular Weight: 372.36

Spacer Length: 11.4 Å

Alternative Names: Suberic acid-2,2,7,7-d4 bis (N-hydroxysuccinimide ester);

DSP-d8

DSP-d8 deuterated protein crosslinker, Dithiobis(succinimidyl 2,2,3,3,6,6,7,7-propionate-d8), is a cell membrane permeable, homobifunctional protein crosslinker containing 8 deuterium atoms to provide an 8 dalton shift by mass spectrometry compared to non-deuterated DSP. DSP-d8 has amine-reactive NHS esters at both ends of a cleavable, 8-atom (12.0 angstrom) spacer arm. DSP-d8 contains a reducible disulfide bond (SS-bond) in the spacer arm. Use the DSP-d8 deuterated protein crosslinking reagent in combination with non-deuterated analog DSP for MS studies

Molecular Weight: 412.46

Spacer Length: 12.0 Å

Alternative Names: Dithiobis(succinimidyl) propionate-d8; DSP-d8

Biotinylation Reagents生物素交联试剂：

产品名称：Biotin Hydrazide

Biotin Hydrazide (Biotin-Hz) is a carbohydrate reactive biotinylation reagent. Biotin Hydrazide is a great choice for labeling mouse monoclonal antibodies, lectins, sugars, unpaired cytosine residues in nucleic acids, and glycoprotiens. Typically, Biotin Hydrazide is used for coupling gly-coproteins through the carbohydrate by hydrazone formation.

Molecular Weight: 258.3

CAS #: 66640-86-6

Spacer Length: 15.7 Å

Alternative Name: (+)-Biotin Hydrazide

产品名称：NHS-Biotin

NHS-Biotin (Succinimidyl Biotin; Succinimidobiotin) is a primary amine reactive biotinylation reagent. The NHS-Biotin molecule is cell membrane permeable and can be used to covalently label intracellular proteins.

Molecular Weight: 341.4

CAS #: 35013-72-0

Spacer Length: 13.5 Å

Alternative Names: Succinimidobiotin; Biotin-OSU; Biotin N-hydroxysuccinimide ester

产品名称：NHS-SS-Biotin

NHS-SS-Biotin, Succinimidyl-2-(biotinamido)-ethyl-1,3'-dithiopropionate, is an amine-reactive biotinylation reagent that contains a reducible disulfide. NHS-SS-Biotin is cell membrane per-meable and has a long chain separating the biotin group from the amino-reactive NHS-ester (N-Hydroxysuccinimide ester). This product is often used to purify an antibody or other protein from a biotin specific affinity resin like immobilized streptavidin without exposing your protein of interest to denaturing conditions.

Molecular Weight: 504.7

CAS #: 142439-92-7

Spacer Length: 24.3 Å

Alternative Name: Biotin disulfide N-Hydroxysuccinimide ester

产品名称：Sulfo-NHS-Biotin

Sulfo-NHS-Biotin (Sulfosuccinimidyl biotin) is a water soluble biotinylation reagent. It is amine reactive and has a spacer arm length of 13.5Å. The Sulfo-NHS-Biotin biotinylation reagent is ideal for biotinylating antibody or protein that can then be used for protein detection or immobi-lization. Sulfo-NHS-Biotin is particularly useful for targeting cell surface proteins.

Molecular Weight: 443.4

CAS #: 119616-92-5

Spacer Length: 13.5 Å

Alternative Names: Biotin 3-sulfo-N-hydroxysuccinimide ester sodium salt;

产品名称：Sulfo-NHS-LC-Biotin

Sulfo-NHS-LC-Biotin, Sulfosuccinimidyl 6-(biotinamido) Hexanoate, is a long chain water solu-ble biotinylation reagent that is reactive toward primary amine groups. Similar to Sulfo-NHS-Biotin (b2100-100mg and b2100-1gm), Sulfo-NHS-LC-Biotin is designed to target cell surface proteins. The sodium sulfonate groups lend water solubility to Sulfo-NHS-LC-Biotin and prevent it from crossing the lipid bi-layer of the cell membrane.

Molecular Weight: 556.6

CAS #: 128062-22-0

Spacer Length: 22.4 Å

Alternative Name: Biotinamidohexanoic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt

产品名称：Sulfo-NHS-SS-Biotin

Sulfosuccinimidyl-2-(biotinamido)-ethyl-1,3'-dithiopropionate (Sulfo-NHS-SS-Biotin) is a cleava-ble, water-soluble, amino-reactive biotinylation reagent. This molecule is cell membrane imper-meable due to its sodium sulfonate group. Sulfo-NHS-SS-Biotin has a long chain spacer arm sep-arating the biotin group from the amino-reactive sulfo-NHS ester moity. It is possible to cleave the biotin group from the crosslinked target protein under reducing conditions, such as in the presence of BME, DTT or TCEP.

Molecular Weight: 606.7

CAS #: 202057-28-1

Spacer Length: 24.3 Å

Alternative Name: Biotin disulfide N-Hydroxysulfosuccinimide ester

Other Modifications其他交联剂产品：

产品名称：HPG

HPG protein modification reagent (p-Hydroxyphenylglyoxal) reacts with arginine residues to give a large increase in absorbance at approximately 340 nm. The HPG is a better choice for ami-no acid side chain modification due to its increased water solubility over phenylglyoxal and im-proved oxidation resistance over p-nitrophenylglyoxal. Chemical Formula: C8H8O4

Molecular Weight: 168.2

CAS #: 24645-80-5

Alternative Names: p-Hydroxyphenylglyoxal monohydrate; 4-hydroxyphenylglyoxal;

产品名称：SATA

SATA (N-Succinimidyl-S-Acetyl-Thioacetate) is a protein modification reagent used to convert primary amine groups into protected sulfhydryls (thiol; -SH). The sulfhydryl is readily made available for use in subsequent reactions after exposure to hydroxylamine.

CAS #: 76931-93-6

Molecular Weight: 231.2

Alternative Names: S-Acetylthioglycolic acid N-hydroxysuccinimide ester

产品名称：Sulfo-NHS Acetate

Sulfo-NHS-Acetate acylating agent (Sulfosuccinimidyl Acetate) is a water soluble. Sulfo-NHS-Acetate irreversibly reacts with primary amines, such as in lysine, at pH greater than 7 to yield the acylated form. Using Sulfo-NHS Acetate prevents polymerization when performing protein crosslinking reactions.

Molecular Weight: 259.17

CAS #: 152305-87-8

Alternative Names: 1-acetyloxy-2,5-dioxopyrrolidine-3-sulfonic acid

产品列表：

Sulfo-NHS    CAS #: 106627-54-7

BS3          CAS #: 82436-77-9

BS2G

BSG          CAS #: 79642-50-5

DSP          CAS #: 57757-57-0

DSS          CAS #: 68528-80-3

DTSSP        CAS #: 81069-02-5

EGS          CAS #: 70539-42-3

Sulfo-EGS    

DSSeb        CAS # 23024-29-5

BMPS         CAS #: 55750-62-4

EMCS         CAS #: 55750-63-5

GMBS         CAS #: 80307-12-6

LC-SPDP             

MBS          CAS #: 58626-38-3

PDPH           

SBA          CAS #: 42014-51-7     

SIA          CAS #: 39028-27-8

SMCC         CAS #: 64987-85-5

SMPB         CAS #: 79886-55-8

SMPH           

SPDP         CAS #: 68181-17-9

Sulfo-LC-SPDP    

Sulfo-MBS    

Sulfo-SANPAH CAS #: 102568-43-4

Sulfo-SMCC   CAS #: 92921-24-9

BS2G-d4

BS3-d4

DSG-d4

DSS-d4

DSP-d8

Biotin Hydrazide CAS #: 66640-86-6

NHS-Biotin       CAS #: 35013-72-0

NHS-SS-Biotin    CAS #: 142439-92-7

Sulfo-NHS-Biotin CAS #: 119616-92-5

Sulfo-NHS-LC-Biotin    CAS #: 128062-22-0

Sulfo-NHS-SS-Biotin    CAS #: 202057-28-1

HPG              CAS #: 24645-80-5

SATA             CAS #: 76931-93-6

Sulfo-NHS Acetate CAS #: 152305-87-8