CHIR-99021 （CT99021） HCl（2mg）_热卖-爱必信（上海）生物科技有限公司

参考价	￥ 680
订货量	≥1

具体成交价以合同协议为准

￥680

≥1

具体成交价以合同协议为准

品牌 absin
型号
厂商性质 生产商
所在地 上海市

属性

$NV_PropertyInfoName.SubString(0,25)

在线询价收藏产品加入对比查看联系电话

更新时间：2024-03-04 07:55:45浏览次数：896评价

联系我们时请说明是化工仪器网上看到的信息，谢谢!

产品分类品牌分类

特色试剂

热卖

激动剂抑制剂

植物提取物

动物提取物

多肽

Forskolin

U0126

SHP099

PD98059

氨基酸

全部产品列表

查看品牌全部分类

产品简介

供货周期	现货	规格	2mg
货号	abs818358

爱必信特色产品线（全部现货）：二抗、标签抗体、对照抗体；WB相关：ECL发光液、预染marker、预制胶；IHC相关：二抗试剂盒、组化笔；IP/CoIP试剂盒；细胞因子、信号通路调节剂；血清、BSA、蛋白酶K、CTB、TTX、CEE；凋亡试剂盒、呼吸爆发试剂盒；动植物提取物...

详细介绍

概述
描述	CHIR-99021 monohydrochloride is a GSK-3α/β inhibitor with IC₅₀ of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases.

性能
保存方法	-20°C
纯度	≥98%
分子量	501.8
化学式	C₂₂H₁₉Cl₃N₈
分子结构式
溶解性	DMSO：93 mg/mL (185.33 mM) Ethanol：2 mg/mL (3.98 mM)
CAS号	1797989-42-4
外观	powder

参考文献
[1]. Ring DB et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes. 2003 Mar;52(3):588-95. [2]. Weikel KA et al. Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells. Biosci Rep. 2016 Sep 16;36(5). [3]. Ai Z et al. CHIR99021 enhances Klf4 Expression through β-Catenin Signaling and miR-7a Regulation in J1 Mouse Embryonic Stem Cells. PLoS One. 2016 Mar 3;11(3) [4]. Preston GC et al. Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes. EMBO J. 2015 Aug 4;34(15):2008-24. [5]. Preston GC et al. Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes. EMBO J. 2015 Aug 4;34(15):2008-24.

参考文献

[1]. Ring DB et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes. 2003 Mar;52(3):588-95.

[2]. Weikel KA et al. Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells. Biosci Rep. 2016 Sep 16;36(5).

[3]. Ai Z et al. CHIR99021 enhances Klf4 Expression through β-Catenin Signaling and miR-7a Regulation in J1 Mouse Embryonic Stem Cells. PLoS One. 2016 Mar 3;11(3)

[4]. Preston GC et al. Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes. EMBO J. 2015 Aug 4;34(15):2008-24.

[5]. Preston GC et al. Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes. EMBO J. 2015 Aug 4;34(15):2008-24.