非受体型酪氨酸蛋白激酶抗体 返回列表页

非受体型酪氨酸蛋白激酶抗体

英文名称 SYK
中文名称 非受体型酪氨酸蛋白激酶抗体
别    名 Tyrosine-protein kinase SYK (Spleen tyrosine kinase) [Contains: 72kDa tyrosine-protein kinase SYK; 40 kDa tyrosine-protein kinase SYK; KSYK_HUMAN.
    
说 明 书 0.1ml  0.2ml  
研究领域 信号转导  细胞凋亡  激酶和磷酸酶  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 72kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SYK
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Syk (72 kDa) is a non receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions. Alternate Names: p72syk; Spleen tyrosine kinase; Tyrosine protein kinase SYK.xy-5651R    phospho-c-Raf(Thr269)磷酸化原癌基因c-Raf抗体
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xy-5653R    Phospho-Rb (Ser612)磷酸化视网膜母细胞瘤相关蛋白1抗体
xy-5665R    Phospho-P105 RB (Ser788)磷酸化视网膜母细胞瘤相关蛋白1抗体
xy-5668R    phospho-RPS6KB1(Ser417)磷酸化核糖体S6蛋白激酶抗体
xy-5670R    phospho-RPS6KB1(Ser427)磷酸化核糖体S6蛋白激酶抗体
xy-5666R    Phospho-Rb (Ser795)磷酸化视网膜母细胞瘤相关蛋白1抗体
xy-5667R    Phospho-Rb (Thr826)磷酸化视网膜母细胞瘤相关蛋白1抗体
xy-5669R    phospho-RPS6KB1(Thr 412) 磷酸化核糖体S6蛋白激酶抗体
xy-5671R    phospho-RPS6KB1(Ser434)磷酸化核糖体S6蛋白激酶抗体
xy-5672R    phospho-RPS6KB1(Ser421)磷酸化核糖体S6蛋白激酶抗体
xy-5673R    phospho-RPS6KB1(Ser441+Thr444)磷酸化核糖体S6蛋白激酶抗体
xy-5674R    phospho-ROCK2(Thr396)磷酸化Rho相关蛋白激酶2抗体
xy-5675R    phospho-ROCK2(Thr249)磷酸化Rho相关蛋白激酶2抗体
xy-5676R    phospho-ROCK2(Tyr256)磷酸化Rho相关蛋白激酶2抗体
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xy-5677R    phospho-RAD51(Thr309)磷酸化Rad51抗体
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xy-5680R    phospho-RPS6KA1(Thr348)磷酸化磷酸化丝氨酸/苏氨酸激酶p90RSK蛋白抗体
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xy-6173R    Rab11ras癌基因家族Rab11蛋白抗体
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xy-6185R    RSPO1分泌性蛋白RSPO1抗体
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xy-6153R    RAC2G蛋白P21 RAC2抗体