调控周期蛋白依赖蛋白激酶SEI1抗体 返回列表页

调控周期蛋白依赖蛋白激酶SEI1抗体

英文名称 Sertad1
中文名称 调控周期蛋白依赖蛋白激酶SEI1抗体
别    名 CDK 4 binding protein p34SEI1; CDK4 binding protein p34SEI; CDK4 binding protein p34SEI1; SEI 1; SEI1; SERTA domain containing 1; SERTA domain containing 1 variant; SERTA domain containing protein 1; Sertad 1; Transcriptional regulator interacting with the PHD bromodomain 1; TRIP Br1; SRTD1_HUMAN.

说 明 书 0.1ml  0.2ml  
研究领域 信号转导  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEI1 (1-35aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
产品介绍 background:
Sertad1 acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a).

Function:
Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a).

Subunit:
Interacts with the PHD-bromodomain of TIF1, TRIM28/TIF1B and p300/CBP. Binds to DP1. Also interacts with CDK4.

Similarity:
Contains 1 SERTA domain.

Database links:
 

UniProtKB/Swiss-Prot: Q9UHV2.2xy-8497R    RENBP肾素结合蛋白抗体
xy-8493R    RFPL2+RFPL3RET指蛋白样2/3抗体
xy-8496R    RFESDRFESD蛋白抗体
xy-8498R    REG1 beta胰岛细胞再生因子β抗体
xy-8376R    RNF160环指蛋白160抗体
xy-8333R    RDH13视黄醇脱氢酶13抗体
xy-8391R    RNF75环指蛋白75抗体
xy-8392R    RIT1RIT1蛋白抗体
xy-9246R    RNF19B环指蛋白19B抗体
xy-8509R    Reg3a胰岛β细胞生长因子抗体
xy-9228R    RNF149环指蛋白149抗体
xy-9230R    RNF158心脏蛋白磷酸酶1结合蛋白/环指蛋白158抗体
xy-9233R    RNF180环指蛋白180抗体
xy-9249R    RNF123环指蛋白123抗体
xy-8499R    RED软骨肉瘤相关蛋白2抗体
xy-8494R    RNF210环指蛋白210抗体
xy-9238R    RNF23环指蛋白23抗体
xy-9239R    RNF24环指蛋白24抗体
xy-9240R    RNF25环指蛋白25抗体
xy-9241R    RNF31环指蛋白31抗体
xy-9242R    RNF34环指蛋白34抗体
xy-9244R    RNF21环指蛋白21抗体
xy-9245R    RNF190环指蛋白190抗体
xy-11355R    RIC8A胆碱酯酶抑制剂8抗体
xy-11356R    ABCA4神经元突触膜胞外分泌调节蛋白1抗体
xy-11357R    RIM2神经元突触膜胞外分泌调节蛋白2抗体
xy-9252R    RNF130环指蛋白130抗体
xy-9609R    RBM26RNA结合蛋白26抗体
xy-9265R    RNF32环指蛋白32抗体
xy-6872R    RING finger protein 189环指蛋白189抗体
xy-7613R    RNF144BE3泛素蛋白连接酶144B/环指蛋白144B抗体