肿瘤坏死因子α诱导蛋白9/前列腺六跨膜上皮抗原4抗体 返回列表页

肿瘤坏死因子α诱导蛋白9/前列腺六跨膜上皮抗原4抗体

英文名称 STEAP4
中文名称 肿瘤坏死因子α诱导蛋白9/前列腺六跨膜上皮抗原4抗体
别    名 alpha-induced protein 9; Metalloreductase STEAP4; six transmembrane prostate protein 2; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STAMP 2; STAMP2; STEA4_HUMAN; STEAP 4; STEAP4; TIARP; TNFAIP 9; TNFAIP9; Tumor necrosis factor; tumor necrosis factor, alpha-induced protein 9; tumor necrosis-alpha-induced adipose-related protein.
  
说 明 书 0.2ml  
研究领域 肿瘤  免疫学  肿瘤细胞生物标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, 
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
细胞定位 细胞浆 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human STEAP4 (85-130aa)
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
产品介绍 background:
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Play a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation.

Function:
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation.

Subunit:
Interacts with and phosphorylates PTK2/FAK1.

Subcellular Location:
Cell membrane. Golgi apparatus membrane; Multi-pass membrane protein.

Tissue Specificity:
Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages.

Similarity:xy-11893R    NELF转录延伸因子NELF抗体
xy-11894R    NELL1蛋白激酶C结合蛋白NELL1抗体
xy-11895R    NELL2蛋白激酶C结合蛋白NELL2抗体
xy-11896R    NETO2脑特异性跨膜蛋白抗体
xy-11898R    NFIA核因子1A抗体
xy-11901R    NHLH1环一螺旋蛋白1抗体
xy-11902R    NME4肿瘤转移抑制基因H4抗体
xy-11903R    神经元衍生孤儿受体1抗体
xy-10065R    Netrin 4轴突生长诱向因子4抗体
xy-10029R    Nectin 4脊髓灰质炎病毒受体相关蛋白4抗体
xy-10037R    NFKB p52细胞核因子/k基因结合核因子 p52/p100抗体
xy-11734R    NDUFS7线粒体复合物NDUFS7蛋白抗体
xy-11736R    NPC2尼曼匹克C2前体蛋白抗体
xy-11738R    Nmnat1烟酰胺腺嘌呤二核苷酸酶1抗体
xy-10197R    nNOS 一氧化氮合成酶-1抗体（神经型）
xy-12314R    NKX6.1转录因子相关蛋白NKX6.1抗体
xy-12345R    NCKAP1L造血蛋白1抗体
xy-10075R    Nidogen2骨巢蛋白抗体
xy-4028R    NUP54NUP54抗体
xy-3695R    NTF97亲核素β1抗体
xy-7124R    NMDA epsilon 1谷氨酸受体NMDAζ1抗体
xy-8483R    NMDA epsilon 2谷氨酸受体NMDAζ2抗体
xy-3692R    Neurogenin 2神经元素2抗体
xy-3688R    NDRG3抑癌基因NDRG3抗体
xy-3682R    有丝分裂氧化酶1抗体
xy-3683R    NADPH oxidase 3NADPH oxidase 3抗体
xy-3684R    NADPH oxidase 4NADPH氧化酶NOX家族的成员4抗体
xy-7714R    CDCA1细胞分裂周期相关蛋白1抗体
xy-2680R    NFAM1NFAM1抗体
xy-11897R    NEURL环指蛋白67抗体
xy-6043R    NBL1神经母细胞瘤抑瘤蛋白1抗体
xy-3886R    NCF1嗜中性粒细胞胞浆因子1抗体
Belongs to the STEAP family.

Database links:
UniProtKB/Swiss-Prot: Q687X5.1