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突触结合蛋白12抗体
英文名称 Synaptotagmin XII
中文名称 突触结合蛋白12抗体
别 名 SRG1; Synaptotagmin 12; Synaptotagmin XII; Synaptotagmin-12; Syt12; SYT12_HUMAN; SytXII.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 神经生物学 信号转导
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Rabbit, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
细胞定位 细胞浆 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Synaptotagmin XII (301-350aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.
Function:
May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
Subunit:
Homodimer. Can also form heterodimersxy-2656R LIR-6白细胞免疫球蛋白样受体6抗体
xy-2646R LAG-3/CD223淋巴细胞活化基因-3抗体
xy-2647R LAIR-1白细胞相关免疫球蛋白样受体1抗体
xy-2650R Langerin/CD207白细胞分化抗原CD207抗体
xy-2655R LTB4-R2白三烯B4受体2抗体
xy-2648R LAIR-2白细胞相关免疫球蛋白样受体2抗体
xy-6069R LLGL1相似肿瘤抑制基因HUGL抗体
xy-6319R IL-1 Beta白介素1β抗体
xy-0814R Beta-lactoglobulinβ-乳球蛋白抗体
xy-12150R LPPR1脂质磷酸磷酸酶相关蛋白1/可塑性相关基因3抗体
xy-12141R LRFN1神经突触粘附样分子1抗体
xy-9327R LRCH1富含亮氨酸重复家庭蛋白1抗体
xy-9330R LRCH4富含亮氨酸重复家庭蛋白4抗体
xy-0109R Leptin receptor(long)瘦素受体抗体(长)
xy-1058R LIF白血病抑制因子抗体
xy-1177R Lingo-1Nogo受体反应蛋白抗体
xy-0738R Livin凋亡抑制蛋白抗体
xy-0821R laminin层粘连蛋白抗体
xy-0759R Lpin1 proteinLpin1 抗体
xy-0760R Lpin1 proteinLpin1 抗体
xy-0816R Lysozyme溶菌酶抗体
xy-0484R Iumbrokinase蚓激酶抗体
xy-0409R Leptin瘦素抗体
xy-0410R Leptin receptor瘦素受体抗体
xy-0109M Leptin receptor(long)瘦素受体抗体(长)
xy-9708R LCE1A晚期包膜蛋白1抗体
xy-6862R LANPL富含亮氨酸样酸性核蛋白抗体
xy-9709R LCE2B晚期包膜蛋白2B抗体
xy-9711R LIPK脂肪酶家庭成员K抗体
xy-1902R Stathmin白血病相关蛋白18/癌蛋白18抗体
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